R M Phillips
Overview
Explore the profile of R M Phillips including associated specialties, affiliations and a list of published articles.
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Articles
113
Citations
968
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Recent Articles
11.
Kazmi N, Hossain M, Phillips R, Al-Mamun M, Bass R
J Theor Biol
. 2012 Sep;
313:142-52.
PMID: 22974970
The potential for the use of in-silico models of disease in progression monitoring is becoming increasingly recognised, as well as its contribution to the development of complete curative processes. In...
12.
McMahon K, Volpato M, Chi H, Musiwaro P, Poterlowicz K, Peng Y, et al.
J Proteome Res
. 2012 Mar;
11(5):2863-75.
PMID: 22416669
Three dimensional multicell tumor spheroids (MCTS) provide an experimental model where the influence of microenvironmental conditions on protein expression can be determined. Sequential trypsin digestion of HT29 colon carcinoma MCTS...
13.
Donnelly O, Errington-Mais F, Steele L, Hadac E, Jennings V, Scott K, et al.
Gene Ther
. 2011 Dec;
20(1):7-15.
PMID: 22170342
Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma....
14.
Phillips R, Merritt T, Goldstein M, Deming D, Slater L, Angeles D
J Perinatol
. 2011 Aug;
32(5):374-80.
PMID: 21836549
Objective: Approximately 40% of women who smoke tobacco quit smoking during pregnancy, yet up to 85% relapse after delivery. Those who resume smoking often do so by 2 to 8...
15.
Phillips R, Bibby M
Methods Mol Med
. 2011 Feb;
46:87-93.
PMID: 21340914
It is becoming increasingly clear that the process of angiogenesis is important for tumor growth and metastasis and as such provides an exploitable target for therapeutic intervention. Consequently a number...
16.
Evans C, Phillips R, Jones P, Loadman P, Sleeman B, Twelves C, et al.
J Theor Biol
. 2009 Feb;
257(4):598-608.
PMID: 19183560
Inadequate drug delivery to tumours is now recognised as a key factor that limits the efficacy of anticancer drugs. Extravasation and penetration of therapeutic agents through avascular tissue are critically...
17.
Alarcon G, Moreland L, Jaffe K, Phillips R, Bocanegra T, Russell I
J Clin Rheumatol
. 2008 Dec;
2(1):6-8.
PMID: 19078020
Whether methotrexate can be safely administered during the perioperative period to rheumatoid arthritis patients undergoing arthroplasties is an issue that has not been resolved to date. We are describing our...
18.
Palit V, Phillips R, Puri R, Shah T, Bibby M
Oncol Rep
. 2005 Sep;
14(4):909-13.
PMID: 16142350
HIF-1 is a heterodimer consisting of the HIF-1alpha and HIF-1beta subunits, and HIF-1alpha is the unique oxygen regulated subunit that determines HIF-1 activity. HIF-1alpha upgrades many gene products which include...
19.
Phillips R
Expert Opin Investig Drugs
. 2005 Jul;
7(6):905-28.
PMID: 15992006
Bioreductive drugs are inactive prodrugs that are converted into potent cytotoxins under conditions of either low oxygen tension or in the presence of high levels of specific reductases. The biochemical...
20.
Airley R, Phillips R, Evans A, Double J, Burger A, Feibig H, et al.
Int J Oncol
. 2005 May;
26(6):1477-84.
PMID: 15870859
Tumour hypoxia confers poor prognosis in a wide range of solid tumours, due to an increased malignancy, increased likelihood of metastasis and treatment resistance. Poorly oxygenated tumours are resistant to...