R M Gubits
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Explore the profile of R M Gubits including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
275
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Recent Articles
1.
Macaya A, Munell F, Gubits R, Burke R
Proc Natl Acad Sci U S A
. 1994 Aug;
91(17):8117-21.
PMID: 7914702
We have previously observed that an axon-sparing injury to the developing striatum induced by the excitotoxin quinolinate results in a decrease in dopaminergic neurons in the substantia nigra pars compacta...
2.
Fujii T, Van Coster R, Old S, Medori R, Winter S, Gubits R, et al.
Ann Neurol
. 1994 Jul;
36(1):83-9.
PMID: 8024267
Two half-brothers and their mother had symptomatic pyruvate dehydrogenase complex deficiency. The infants had severe congenital lactic acidosis, seizures, and apneic spells and died at the ages 3 and 4...
3.
Munell F, Burke R, Bandele A, Gubits R
Brain Res Dev Brain Res
. 1994 Jan;
77(1):111-21.
PMID: 8131258
The sites of expression of early response mRNAs were determined in the brains of 7-day-old rat pups exposed to unilateral carotid artery ligation followed by 3 h of hypoxia. Pups...
4.
Gubits R, Geard C, Schiff P
Int J Radiat Oncol Biol Phys
. 1993 Oct;
27(3):637-42.
PMID: 7901186
Purpose: The promising chemotherapeutic agent, taxol, has been shown to sensitize the G18 line of human astrocytoma cells to ionizing radiation. The present studies were performed to identify specific changes...
5.
Gubits R, Burke R, Bandele A, Munell F
Brain Res Mol Brain Res
. 1993 May;
18(3):228-38.
PMID: 7684483
Immediate early gene (IEG) products, such as FOS and JUN, may partially mediate the long-term transcriptional response of CNS cells to specific changes in their environment. To determine whether IEG...
6.
Gubits R, Yu H, Casey G, Munell F, Vitek M
J Neurosci Res
. 1992 Oct;
33(2):297-305.
PMID: 1333540
Previous studies have demonstrated variability in the phenotype of rat C6 glioma cells. In the present study, we compared morphology, growth rate, and beta-adrenergic regulation of gene expression in early...
7.
Gubits R, Yu H
J Neurosci Res
. 1991 Dec;
30(4):625-30.
PMID: 1686282
The AP1 transcriptional complex is a heterodimer composed of proteins encoded by the fos and jun proto-oncogene families. Changes in the concentration and composition of AP1 occur after cells are...
8.
Gubits R, Wollack J, Yu H, Liu W
Brain Res Mol Brain Res
. 1990 Oct;
8(4):275-81.
PMID: 2176706
Extracellular adenosine acts through specific cell surface receptors to modulate numerous physiological processes in both the CNS and peripheral tissues (e.g. neurotransmitter release and blood flow). Activation of A1 or...
9.
Tjaden G, Aguanno A, Kumar R, Benincasa D, Gubits R, Yu H, et al.
Mol Cell Biol
. 1990 Jun;
10(6):3277-9.
PMID: 2160599
Nerve growth factor (NGF) affects levels of the alpha subunit of the stimulatory G protein (Gs-alpha) in pheochromocytoma 12 cells in a bidirectional, density-dependent manner. Cells grown at high density...
10.
Gubits R, Smith T, Fairhurst J, Yu H
Brain Res Mol Brain Res
. 1989 Jul;
6(1):39-45.
PMID: 2570340
Recent evidence supports a role for transient c-fos expression as one step in signalling pathways by which membrane receptor-ligand interactions are transduced into appropriate intracellular responses. The activity of adrenergic...