R L Wilder
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Explore the profile of R L Wilder including associated specialties, affiliations and a list of published articles.
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203
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5283
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Recent Articles
11.
Elenkov I, Wilder R, Chrousos G, Vizi E
Pharmacol Rev
. 2000 Dec;
52(4):595-638.
PMID: 11121511
The brain and the immune system are the two major adaptive systems of the body. During an immune response the brain and the immune system "talk to each other" and...
12.
Cutolo M, Wilder R
Rheum Dis Clin North Am
. 2000 Nov;
26(4):825-39.
PMID: 11084946
It is now documented that androgens and estrogens modulate susceptibility and progression to autoimmune rheumatic diseases. At any concentration, androgens seem to be primarily suppressive on cellular and humoral immunity,...
13.
Kanik K, Wilder R
Rheum Dis Clin North Am
. 2000 Nov;
26(4):805-23.
PMID: 11084945
A number of hormonal abnormalities are present in RA patients. A major theme of these abnormalities seems to be that deficiencies in the production or action of gonadal (estrogens and...
14.
Goldbach-Mansky R, Lee J, McCoy A, Hoxworth J, Yarboro C, Smolen J, et al.
Arthritis Res
. 2000 Nov;
2(3):236-43.
PMID: 11056669
STATEMENT OF FINDINGS: An inception cohort of 238 patients having peripheral joint synovitis of less than 12 months duration was evaluated clinically and followed prospectively for 1 year to determine...
15.
Joe B, Remmers E, Dobbins D, Salstrom J, Furuya T, Dracheva S, et al.
Immunogenetics
. 2000 Sep;
51(11):930-44.
PMID: 11003387
Rat Chromosome 10 (RNO10) harbors Cia5, a non-MHC quantitative trait locus (QTL) that regulates the severity of type II collagen-induced arthritis (CIA) in DAxF344 and DAxBN F2 rats. CIA is...
16.
Furuya T, Salstrom J, Cannon G, Joe B, Remmers E, Griffiths M, et al.
Hum Mol Genet
. 2000 Sep;
9(15):2241-50.
PMID: 11001927
Rheumatoid arthritis (RA) is a common, chronic, autoimmune, inflammatory disease that is influenced by genetic factors including gender. Many studies suggest that the genetic risk for RA is determined by...
17.
Griffiths M, Wang J, Joe B, Dracheva S, Kawahito Y, Shepard J, et al.
Arthritis Rheum
. 2000 Jun;
43(6):1278-89.
PMID: 10857786
Objective: Collagen-induced arthritis (CIA) is a polygenic model of experimentally induced autoimmunity and chronic joint inflammation. This study maps genetic loci that regulate CIA susceptibility in DA/Bkl (DA) and BN/SsNHsd...
18.
Kanik K, Chrousos G, Schumacher H, Crane M, Yarboro C, Wilder R
J Clin Endocrinol Metab
. 2000 Apr;
85(4):1461-6.
PMID: 10770182
To determine whether alterations in adrenocortical function occur early in the development of inflammatory joint disease, we examined patients with new onset synovitis (<1 yr) prior to treatment with corticosteroids...
19.
Torpy D, Papanicolaou D, Lotsikas A, Wilder R, Chrousos G, Pillemer S
Arthritis Rheum
. 2000 Apr;
43(4):872-80.
PMID: 10765933
Objective: To determine whether deficient activity of the hypothalamic corticotropin-releasing hormone (CRH) neuron, which stimulates the hypothalamic-pituitary-adrenal (HPA) axis and the central control nuclei of the sympathetic nervous system and...
20.
Dracheva S, Remmers E, Chen S, Chang L, Gulko P, Kawahito Y, et al.
Genomics
. 2000 Feb;
63(2):202-26.
PMID: 10673333
The rat (Rattus norvegicus) is an important experimental model for many human diseases including arthritis, diabetes, and other autoimmune and chronic inflammatory diseases. The rat genetic linkage map, however, is...