R L Wendt
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Explore the profile of R L Wendt including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
112
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Recent Articles
1.
Lee K, Greenwood J, Wendt R, Lappe R
Am J Hypertens
. 1990 Apr;
3(4):262-7.
PMID: 2140688
The renal and hemodynamic responses to intravenous anaritide, a human atrial natriuretic factor [102-126] at 0.3 to 20 micrograms/kg in conscious rhesus monkeys with and without acute extracellular hypervolemia were...
2.
Silver P, FENICHEL R, Wendt R
J Cardiovasc Pharmacol
. 1988 Mar;
11(3):299-307.
PMID: 2452922
Arylalkylsulfonamides, identified as Wy-46,622 and Wy-47,324, combine pharmacological properties of the Ca2+ entry blocker verapamil and the calmodulin antagonist W-7. These agents directly inhibit arterial actin-myosin interactions via inhibition of...
3.
Lappe R, Todt J, Wendt R
Am J Hypertens
. 1988 Jan;
1(1):47-9.
PMID: 3259432
Calcitonin gene-related peptide (CGRP) is a potent peripheral vasodilator. In the present study, the cardiovascular effects of centrally administered CGRP were examined in conscious, normotensive rats. The rats were chronically...
4.
Lappe R, Slivjak M, Todt J, Wendt R
Regul Pept
. 1987 Dec;
19(5-6):307-12.
PMID: 3501866
The cardiovascular effects of calcitonin gene-related peptide (CGRP) were examined in conscious, unrestrained rats. Changes in mean arterial pressure, heart rate and cardiac output were continuously monitored before and after...
5.
Lappe R, Todt J, Wendt R
Peptides
. 1987 Jul;
8(4):747-9.
PMID: 3498157
In the present study the regional hemodynamic effects of CGRP were examined in conscious unrestrained spontaneously hypertensive rats (SHR). The animals were chronically instrumented with miniaturized pulsed Doppler flow probes...
6.
Lappe R, Todt J, Wendt R
Circ Res
. 1987 Jul;
61(1):134-40.
PMID: 3038365
Previous studies have indicated that the hypotensive effects of atrial natriuretic factor were enhanced in renin-dependent hypertensive rats, suggesting that the atrial peptides may antagonize the vasoconstrictor effects of the...
7.
Colatsky T, Bird L, Jurkiewicz N, Wendt R
J Cardiovasc Pharmacol
. 1987 Apr;
9(4):435-44.
PMID: 2438506
Recainam, [N-2,6-dimethylphenyl-N'-3-(1-methylethyl-amino)propylurea] hydrochloride (Wy-42,362), is a new class I antiarrhythmic agent that has been shown to be very effective in suppressing premature ventricular contractions in humans. To clarify the mechanism...
8.
Lee K, Rodzinski J, Bex F, Lappe R, Wendt R
Clin Exp Pharmacol Physiol
. 1987 Feb;
14(2):137-40.
PMID: 2886239
The hemodynamic responses to i.v. infusion of 0.3 and 0.6 microgram/kg per min of human atrial natriuretic factor (hANF [102-126]) in intact, conscious, one-kidney, perinephritic, hypertensive beagles were examined and...
9.
Silver P, SULKOWSKI T, Lappe R, Wendt R
J Cardiovasc Pharmacol
. 1986 Nov;
8(6):1168-75.
PMID: 2434743
1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-4-(pentafluorophenyl)-1,7- naphthyridine-3-carboxylic acid methyl ester hydrochlorides with either a 3-phenoxy-2-hydroxypropyl (Wy-46,300) or 2-hydroxy-4-phenylbutyl (Wy-46,531) substituent at the 7 position are structurally novel vascular relaxant compounds which lower blood pressure by...
10.
Lappe R, Todt J, Wendt R
Hypertension
. 1986 Oct;
8(10):866-73.
PMID: 2944826
The cardiovascular responses to intravenous bolus administration of several synthetic atrial natriuretic peptides were examined in conscious spontaneously hypertensive rats and compared with the hemodynamic effects of continuous infusions of...