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R L Shoeman

Explore the profile of R L Shoeman including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 662
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Recent Articles
1.
Sorigue D, Hadjidemetriou K, Blangy S, Gotthard G, Bonvalet A, Coquelle N, et al.
Science . 2021 Apr; 372(6538). PMID: 33833098
Fatty acid photodecarboxylase (FAP) is a photoenzyme with potential green chemistry applications. By combining static, time-resolved, and cryotrapping spectroscopy and crystallography as well as computation, we characterized FAP reaction intermediates...
2.
Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R, et al.
Nat Commun . 2020 Feb; 11(1):620. PMID: 32001697
Sleeping sickness is a fatal disease caused by the protozoan parasite Trypanosoma brucei (Tb). Inosine-5'-monophosphate dehydrogenase (IMPDH) has been proposed as a potential drug target, since it maintains the balance...
3.
Schulz J, Bielecki J, Doak R, Dorner K, Graceffa R, Shoeman R, et al.
J Synchrotron Radiat . 2019 Mar; 26(Pt 2):339-345. PMID: 30855241
The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible...
4.
Feng Y, Alonso-Mori R, Barends T, Blank V, Botha S, Chollet M, et al.
J Synchrotron Radiat . 2015 May; 22(3):626-33. PMID: 25931078
Multiplexing of the Linac Coherent Light Source beam was demonstrated for hard X-rays by spectral division using a near-perfect diamond thin-crystal monochromator operating in the Bragg geometry. The wavefront and...
5.
Starodub D, Aquila A, Bajt S, Barthelmess M, Barty A, Bostedt C, et al.
Nat Commun . 2012 Dec; 3:1276. PMID: 23232406
Diffractive imaging with free-electron lasers allows structure determination from ensembles of weakly scattering identical nanoparticles. The ultra-short, ultra-bright X-ray pulses provide snapshots of the randomly oriented particles frozen in time,...
6.
Loh N, Hampton C, Martin A, Starodub D, Sierra R, Barty A, et al.
Nature . 2012 Jun; 486(7404):513-7. PMID: 22739316
The morphology of micrometre-size particulate matter is of critical importance in fields ranging from toxicology to climate science, yet these properties are surprisingly difficult to measure in the particles' native...
7.
Martin A, Loh N, Hampton C, Sierra R, Wang F, Aquila A, et al.
Opt Express . 2012 Jun; 20(12):13501-12. PMID: 22714377
The emergence of femtosecond diffractive imaging with X-ray lasers has enabled pioneering structural studies of isolated particles, such as viruses, at nanometer length scales. However, the issue of missing low...
8.
Loh N, Bogan M, Elser V, Barty A, Boutet S, Bajt S, et al.
Phys Rev Lett . 2010 Sep; 104(22):225501. PMID: 20867179
We reconstructed the 3D Fourier intensity distribution of monodisperse prolate nanoparticles using single-shot 2D coherent diffraction patterns collected at DESY's FLASH facility when a bright, coherent, ultrafast x-ray pulse intercepted...
9.
Tolstonog G, MOTHES E, Shoeman R, Traub P
DNA Cell Biol . 2001 Dec; 20(9):531-54. PMID: 11747605
Crosslinkage of vimentin to DNA in mouse L929 cells by formaldehyde and isolation of SDS-stable DNA-vimentin complexes from normal L929 cells and mouse and human embryo fibroblasts indicated close spatial...
10.
Tolstonog G, Shoeman R, Traub U, Traub P
DNA Cell Biol . 2001 Dec; 20(9):509-29. PMID: 11747604
Because knockout of the vimentin gene in mice did not produce an immediately obvious, overt, or lethal specific phenotype, the conjecture was made that the mutation affects some subtle cellular...