R L Moritz
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Explore the profile of R L Moritz including associated specialties, affiliations and a list of published articles.
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Articles
81
Citations
1961
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Recent Articles
1.
Reales-Calderon J, Sun Z, Mascaraque V, Perez-Navarro E, Vialas V, Deutsch E, et al.
J Proteomics
. 2021 Mar;
239:104192.
PMID: 33757883
Pseudomonas aeruginosa is an important opportunistic human pathogen with high prevalence in nosocomial infections. This microorganism is a good model for understanding biological processes such as the quorum-sensing response, the...
2.
Varghese J, Moritz R, van Donkelaar A, Ji H, Ivancic N, Branson K, et al.
Proc Natl Acad Sci U S A
. 2002 Dec;
99(25):15959-64.
PMID: 12461182
Dysregulated production of IL-6 and its receptor (IL-6R) are implicated in the pathogenesis of multiple myeloma, autoimmune diseases and prostate cancer. The IL-6R complex comprises two molecules each of IL-6,...
3.
Hoffmann P, Ji H, Moritz R, Connolly L, Frecklington D, Layton M, et al.
Proteomics
. 2001 Aug;
1(7):807-18.
PMID: 11503205
The conventional approach for analyzing the protein complement of a genome involves the combination of two-dimensional gel electrophoresis (2-DE) and mass spectrometric based protein identification technologies. While 2-DE is a...
4.
Pouliot N, Connolly L, Moritz R, Simpson R, Burgess A
Exp Cell Res
. 2000 Dec;
261(2):360-71.
PMID: 11112342
Epidermal growth factor (EGF) receptor ligands such as EGF and transforming growth factor-alpha (TGF-alpha) play an important role in controlling the proliferation, survival, morphology, and motility of colonic epithelial cells....
5.
Moritz R, Hall N, Connolly L, Simpson R
J Biol Chem
. 2000 Dec;
276(11):8244-53.
PMID: 11098061
gp130 is the common signal transducing receptor subunit for the interleukin-6-type family of cytokines. Its extracellular region (sgp130) is predicted to consist of five fibronectin type III-like domains and an...
6.
Verhagen A, Ekert P, Pakusch M, Silke J, Connolly L, Reid G, et al.
Cell
. 2000 Aug;
102(1):43-53.
PMID: 10929712
To identify proteins that bind mammalian IAP homolog A (MIHA, also known as XIAP), we used coimmuno-precipitation and 2D immobilized pH gradient/SDS PAGE, followed by electrospray ionization tandem mass spectrometry....
7.
Simpson R, Connolly L, Eddes J, Pereira J, Moritz R, Reid G
Electrophoresis
. 2000 Jun;
21(9):1707-32.
PMID: 10870958
The proteomic definition of plasma membrane proteins is an important initial step in searching for novel tumor marker proteins expressed during the different stages of cancer progression. However, due to...
8.
Moritz R, Ward L, Tu G, Fabri L, Ji H, Yasukawa K, et al.
Growth Factors
. 1999 Jul;
16(4):265-78.
PMID: 10427501
Interleukin-6 (IL-6) mediates its activity through binding to two cell-surface receptors. The high-affinity human IL-6 receptor complex consists of two transmembrane anchored subunits: a ligand-specific, low-affinity IL-6 receptor and the...
9.
Castellanos-Serra L, Proenza W, Huerta V, Moritz R, Simpson R
Electrophoresis
. 1999 May;
20(4-5):732-7.
PMID: 10344241
Identification and characterization of proteins isolated from natural sources by polyacrylamide gel electrophoresis has become a routine technique. However, efficient sample proteolysis and subsequent peptide extraction is still problematic. Here,...
10.
Cole A, Hall N, Treutlein H, Eddes J, Reid G, Moritz R, et al.
J Biol Chem
. 1999 Mar;
274(11):7207-15.
PMID: 10066782
The high affinity interleukin-6 (IL-6) receptor is a hexameric complex consisting of two molecules each of IL-6, IL-6 receptor (IL-6R), and the high affinity converter and signaling molecule, gp130. The...