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R L MCKEE

Explore the profile of R L MCKEE including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 33
Citations 151
Followers 0
Related Specialties
Endocrinology
Chemistry
Biochemistry
Top 10 Co-Authors
M P Caulfield
M Rosenblatt
J J Levy
M E Goldman
J E Fisher
J E Reagan
E Roubini
M Chorev
S W Gibbons
V J Hruby
Published In
Endocrinology
Biochemistry
J Am Chem Soc
J Org Chem
Int J Pept Protein Res
Affiliations
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Recent Articles
1.
Antibacterial action of three quinazolines
THAYER J, GRAVATT M, MAGNUSON H, MCKEE R
Antibiot Chemother (Northfield) . 2014 Feb; 2(9):463-6. PMID: 24542082
No abstract available.
2.
Some derivatives of 3-amino-4-(1-diethylamino-4-pentylamino)-chlorobenzene
MCKEE R, McKEE M, BOST R
J Am Chem Soc . 2010 Oct; 68(10):1904. PMID: 21001114
No abstract available.
3.
Some basically substituted quinazolines
MCKEE R, McKEE M, BOST R
J Am Chem Soc . 2010 Oct; 68(10):1902. PMID: 21001113
No abstract available.
4.
para-Substituted phenyl isothiocyanates and some related thioureas
MCKEE R, BOST R
J Am Chem Soc . 2010 Mar; 68(12):2506. PMID: 20282387
No abstract available.
5.
Inactivation by plasma may be responsible for lack of efficacy of parathyroid hormone antagonists in hypercalcemia of malignancy
Kukreja S, DAnza J, Wimbiscus S, Fisher J, MCKEE R, Caulfield M, et al.
Endocrinology . 1994 May; 134(5):2184-8. PMID: 8156920
PTH-related protein (PTHrP) has been shown to be a major factor responsible for hypercalcemia of malignancy. PTHrP acts via the PTH/PTHrP receptor, and therefore, PTH antagonists might be expected to...
6.
A novel, mild, specific and indirect maleimido-based radioiodolabeling method. Radiolabeling of analogs derived from parathyroid hormone (PTH) and PTH-related protein (PTHrP)
Chorev M, Caulfield M, Roubini E, MCKEE R, Gibbons S, Leu C, et al.
Int J Pept Protein Res . 1992 Nov; 40(5):445-55. PMID: 1336486
In an effort to design a mild, non-oxidative and site-specific means of radiolabeling bioactive molecules we have employed maleimido-sulfhydryl chemistry to produce bioactive hormone radioligands. We have prepared two novel...
7.
A pharmacological comparison of parathyroid hormone receptors in human bone and kidney
Orloff J, Ribaudo A, MCKEE R, Rosenblatt M, Stewart A
Endocrinology . 1992 Oct; 131(4):1603-11. PMID: 1327716
While abundant information is available characterizing PTH receptor properties in other species, data on human PTH receptors is very limited. We have been interested in the possibility that tissue-specific differences...
8.
Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by down-regulating parathyroid hormone receptors
Katz M, Gutierrez G, Mundy G, Hymer T, Caulfield M, MCKEE R
J Cell Physiol . 1992 Oct; 153(1):206-13. PMID: 1325978
The effects of the monokines tumor necrosis factor alpha (TNF) and interleukin 1 (IL 1) on parathyroid hormone (PTH)-responsive adenylate cyclase were examined in clonal rat osteosarcoma cells (UMR-106) with...
9.
Expression of the parathyroid hormone-related protein gene in the avian oviduct: potential role as a local modulator of vascular smooth muscle tension and shell gland motility during the egg-laying cycle
Thiede M, Harm S, MCKEE R, Grasser W, Duong L, Leach Jr R
Endocrinology . 1991 Oct; 129(4):1958-66. PMID: 1845356
The phylogenetic conservation of the primary structure of PTH-related protein (PTHrP) supports an important, yet undetermined, role(s) for this molecule in the biology of birds and mammals. As an initial...
10.
Solid-phase synthesis and biologic activity of human parathyroid hormone (1-84)
Goud N, MCKEE R, Sardana M, DeHaven P, Huelar E, Syed M, et al.
J Bone Miner Res . 1991 Aug; 6(8):781-9. PMID: 1664643
We have chemically synthesized the full-length, 84 amino acid, human parathyroid hormone (hPTH) on a greater than 100 mg scale by the Merrifield solid-phase technique of stepwise peptide synthesis using...