R Kris
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Explore the profile of R Kris including associated specialties, affiliations and a list of published articles.
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15
Citations
781
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Recent Articles
1.
Lee M, Draoui M, Zia F, Gazdar A, Oie H, Bepler G, et al.
J Natl Cancer Inst Monogr
. 1992 Jan;
(13):117-23.
PMID: 1327029
The ability of monoclonal antibody (MAb 108), an immunoglobulin G (IgG)2a against the epidermal growth factor receptor (EGF-R), to interact with lung cancer cell lines was investigated. 125I-EGF bound with...
2.
Cyr C, Huebner K, Druck T, Kris R
Biochem Biophys Res Commun
. 1991 Nov;
181(1):184-90.
PMID: 1659806
A cDNA clone encoding a human endothelin receptor was isolated from a placenta cDNA library. The deduced amino acid sequence of the clone is 94% identical to the bovine endothelin...
3.
Cirillo D, Naldini L, Moody T, Comoglio P, Schlessinger J, Kris R
Peptides
. 1990 Jul;
11(4):737-45.
PMID: 2172941
Properties of detergent solubilized gastrin-releasing peptide receptor were investigated. Swiss 3T3 membranes were covalently labeled with [125I]GRP and homobifunctional cross-linkers. A major labeled protein of 75 kDa was resolved using...
4.
Naldini L, Cirillo D, Moody T, Comoglio P, Schlessinger J, Kris R
Biochemistry
. 1990 May;
29(21):5153-60.
PMID: 2165804
The receptor for the neuropeptide gastrin-releasing peptide, the mammalian homologue of bombesin, was solubilized from rat brain and Swiss 3T3 cells by using the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid (CHAPS) and...
5.
Bellot F, Moolenaar W, Kris R, Mirakhur B, Verlaan I, Ullrich A, et al.
J Cell Biol
. 1990 Feb;
110(2):491-502.
PMID: 2298813
We have tested the effects of an mAb directed against the protein core of the extracellular domain of the human EGF receptor (mAb108), on the binding of EGF, and on...
6.
Ennis B, Valverius E, Bates S, Lippman M, Bellot F, Kris R, et al.
Mol Endocrinol
. 1989 Nov;
3(11):1830-8.
PMID: 2608059
The response of malignant and nonmalignant human breast cell lines to the growth inhibitory effects of monoclonal antibodies against the epidermal growth factor (EGF) receptor was studied. A series of...
7.
Margolis B, Lax I, Kris R, Dombalagian M, Honegger A, Howk R, et al.
J Biol Chem
. 1989 Jun;
264(18):10667-71.
PMID: 2543678
Activation of the epidermal growth factor (EGF) receptor kinase leads to autophosphorylation and to the phosphorylation of various cellular substrates. The three known autophosphorylation sites of EGF receptor are located...
8.
Moody T, Mahmoud S, Staley J, Naldini L, Cirillo D, South V, et al.
J Mol Neurosci
. 1989 Jan;
1(4):235-42.
PMID: 2561955
Bombesin/gastrin-releasing peptide receptors were characterized in human glioblastoma cell lines. [125I]Gastrin-releasing peptide or ([125I]Tyr4)bombesin bound with high affinity to these cell lines. Binding to cell line U-118 was time dependent,...
9.
Honegger A, Dull T, Szapary D, Komoriya A, Kris R, Ullrich A, et al.
EMBO J
. 1988 Oct;
7(10):3053-60.
PMID: 3181128
Epidermal growth factor (EGF)-receptor mutants in which individual autophosphorylation sites (Tyr1068, Tyr1148 or Tyr1173) have been replaced by phenylalanine residues were expressed in NIH-3T3 cells lacking endogenous EGF-receptors. Kinetic parameters...
10.
Tal M, Wetzler M, Josefberg Z, Deutch A, Gutman M, Assaf D, et al.
Cancer Res
. 1988 Mar;
48(6):1517-20.
PMID: 3345525
The HER2/neu protooncogene was found to be amplified in 6 of 109 primary adenocarcinoma tumors. No HER2/neu amplification was found in 29 other primary nonadenocarcinomatous tumors. In two colon tumors,...