R Keith Reeves
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Explore the profile of R Keith Reeves including associated specialties, affiliations and a list of published articles.
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108
Citations
2427
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Recent Articles
1.
Hudson A, Wu P, Kroll K, Hueber B, Woolley G, Shi P, et al.
J Virol
. 2025 Feb;
:e0163424.
PMID: 39912635
Importance: Despite significant advances in antiretroviral therapy and pre-exposure prophylaxis, HIV remains a global challenge. Understanding the underlying immune mechanisms is critical for improving HIV control and therapeutic development. Cellular...
2.
Nohara J, Evangelous T, Berry M, Beck W, Mudrak S, Jha S, et al.
Pathog Immun
. 2025 Feb;
10(1):49-79.
PMID: 39911143
Background: Antibody-dependent cell-mediated cytotoxic (ADCC) response mediated by natural killer (NK) cells correlates with decreased infection risk in studies involving simian immunodeficiency virus (SIV)/simian-human immunodeficiency virus (SHIV), and human immunodeficiency...
3.
Jost S, Reeves R
Curr Opin HIV AIDS
. 2025 Jan;
20(2):109-116.
PMID: 39773904
Purpose Of Review: Like elephants (and T cells), accumulating evidence suggest natural killer (NK) cells never forget. The description of adaptive or memory NK cells, which can be induced by...
4.
Semmes E, Nettere D, Nelson A, Hurst J, Cain D, Burt T, et al.
J Clin Invest
. 2024 Nov;
135(1).
PMID: 39531313
Human cytomegalovirus (HCMV) profoundly impacts host T and NK cells across the lifespan, yet how this common congenital infection modulates developing fetal immune cell compartments remains underexplored. Using cord blood...
5.
Kahan R, Abraham N, Lee H, Ettenger R, Grimm P, Reed E, et al.
Pediatr Transplant
. 2024 Nov;
28(8):e14877.
PMID: 39508125
Background: Natural killer (NK) cells have gained recognition for playing an integral role in both alloimmunity and protective immunity, particularly viral infection control, in solid organ transplantation. Using data from...
6.
Blass E, Colarusso A, Aid M, Larocca R, Reeves R, Barouch D
bioRxiv
. 2024 Oct;
PMID: 39464013
As the first responder to immunological challenges, the innate immune system shapes and regulates the ensuing adaptive immune response. Many clinical studies evaluating the role of innate immunity in initiating...
7.
Balachandran H, Kroll K, Terry K, Manickam C, Jones R, Woolley G, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012439.
PMID: 39133756
Natural killer (NK) cells play a critical role in virus control. However, it has remained largely unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic. To address...
8.
Sugawara S, Lee E, Craemer M, Pruitt A, Balachandran H, Gressens S, et al.
AIDS Res Hum Retroviruses
. 2024 Jul;
40(11):631-636.
PMID: 39041622
Multifaceted natural killer (NK) cell activities are indispensable for controlling human immunodeficiency virus (HIV)-1 transmission and pathogenesis. Among the diverse functions of NK cells, antibody-dependent cellular cytotoxicity (ADCC) has been...
9.
Woolley G, Kroll K, Hoffman K, Ward A, Corneli A, Mudrak S, et al.
AIDS Res Hum Retroviruses
. 2024 May;
40(10):549-554.
PMID: 38753709
Climate change poses one of the most significant modern threats to overall human health,especially for vulnerable populations including persons living with HIV (PLWH). In this perspective, we specifically explore the...
10.
Manickam C, Upadhyay A, Woolley G, Kroll K, Terry K, Broedlow C, et al.
PLoS Pathog
. 2024 May;
20(5):e1012223.
PMID: 38739675
Natural killer-like B (NKB) cells are unique innate immune cells expressing both natural killer (NK) and B cell receptors. As first responders to infection, they secrete IL-18 to induce a...