R K B Pearce
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Explore the profile of R K B Pearce including associated specialties, affiliations and a list of published articles.
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29
Citations
747
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Recent Articles
1.
Alexandris A, Walker L, Liu A, McAleese K, Johnson M, Pearce R, et al.
Neuropathol Appl Neurobiol
. 2019 Aug;
46(3):264-278.
PMID: 31454423
Aims: Galanin is a highly inducible neuroprotective neuropeptide and in Alzheimer's disease (AD), a network of galaninergic fibres has been reported to hypertrophy and hyperinnervate the surviving cholinergic neurons in...
2.
Liu A, Lim E, Ahmed I, Chang R, Pearce R, Gentleman S
Neuropathol Appl Neurobiol
. 2018 Jul;
44(7):647-662.
PMID: 30005126
Although the nucleus of the vertical limb of the diagonal band of Broca (nvlDBB) is the second largest cholinergic nucleus in the basal forebrain, after the nucleus basalis of Meynert,...
3.
Williams M, Sharma P, MacDonald C, Pearce R, Hirsch S, Maier M
Eur Arch Psychiatry Clin Neurosci
. 2018 Jul;
269(4):387-395.
PMID: 29980921
The corpus callosum has become a key area of interest for researchers in severe mental illness. Disruptions in fractional anisotropy in the callosum have been reported in schizophrenia and major...
4.
Liu A, Hurry M, Ng O, DeFelice J, Lai H, Pearce R, et al.
Neuropathol Appl Neurobiol
. 2015 Nov;
42(6):573-87.
PMID: 26526972
Aims: CLARITY is a novel technique which enables three-dimensional visualization of immunostained tissue for the study of circuitry and spatial interactions between cells and molecules in the brain. In this...
5.
Williams M, Sharma P, Fung K, Pearce R, Hirsch S, Maier M
Psychol Med
. 2015 Feb;
45(10):2145-55.
PMID: 25712170
Background: Abnormalities in the anterior inter-hemispheric connectivity have previously been implicated in major depressive disorder. Disruptions in fractional anisotropy in the callosum and fornix have been reported in schizophrenia and...
6.
Williams M, Galvin K, OSullivan B, MacDonald C, Ching E, Turkheimer F, et al.
Eur Arch Psychiatry Clin Neurosci
. 2013 Dec;
264(4):285-96.
PMID: 24374935
Schizophrenia is a chronic, disabling neuropsychiatric disorder characterised by positive, negative and cognitive symptoms. The aetiology is not known, although genetic, imaging and pathological studies have implicated both neurodevelopmental and...
7.
Jackson M, Swart T, Pearce R, Jenner P
J Neural Transm (Vienna)
. 2013 Aug;
121(2):163-9.
PMID: 23959162
Anti-cholinergic drugs are used in the treatment of Parkinson’s disease (PD) and they can improve motor disability in some patients and may alter the expression of dyskinesia. We report the...
8.
Williams M, Harb H, Pearce R, Hirsch S, Maier M
Schizophr Res
. 2013 May;
147(2-3):402-3.
PMID: 23639671
No abstract available.
9.
Kalaitzakis M, Gentleman S, Pearce R
Neuropathol Appl Neurobiol
. 2013 Feb;
39(6):644-53.
PMID: 23363035
Aims: Abnormal sleep is a common feature of Parkinson's disease (PD) and prodromal disorders of sleep are frequent (e.g. restless legs syndrome and rapid eye movement sleep behaviour disorder). However,...
10.
Williams M, Marsh R, MacDonald C, Jain J, Pearce R, Hirsch S, et al.
Eur Arch Psychiatry Clin Neurosci
. 2012 Dec;
263(6):485-95.
PMID: 23229688
The nucleus basalis has not been examined in detail in severe mental illness. Several studies have demonstrated decreases in glia and glial markers in the cerebral cortex in schizophrenia, familial...