R J Wills
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Explore the profile of R J Wills including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
328
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Recent Articles
1.
Clewell 3rd H, Andersen M, Wills R, Latriano L
J Am Acad Dermatol
. 1997 Mar;
36(3 Pt 2):S77-85.
PMID: 9091511
Background: A physiologically based pharmacokinetic (PBPK) model for all-trans-retinoic acid (tretinoin) was developed to provide a coherent description of tretinoin absorption, distribution metabolism, and excretion across species and routes of...
2.
Latriano L, Tzimas G, Wong F, Wills R
J Am Acad Dermatol
. 1997 Mar;
36(3 Pt 2):S37-46.
PMID: 9091507
Background: The percutaneous absorption of topically applied tretinoin cream and emollient cream formulations has not been comprehensively studied. Objective: To assess tretinoin absorption and plasma levels of tretinoin and its...
3.
Wills R, Ferraiolo B
Clin Pharmacokinet
. 1992 Dec;
23(6):406-14.
PMID: 1458760
No abstract available.
4.
Walbergh E, Wills R, Eckhert J
Anesthesiology
. 1991 Feb;
74(2):233-5.
PMID: 1990898
Nasally administered midazolam appears to be a useful method for rapidly sedating children prior to the induction of anesthesia. We determined the peak plasma concentrations after intranasal administration of midazolam...
5.
Wills R
Clin Pharmacokinet
. 1990 Nov;
19(5):390-9.
PMID: 1702693
Interferons are a family of proteins shown to be effective in the treatment of viral (condylomata, acuminata) and neoplastic (hairy cell leukaemia and AIDS-related Kaposi's sarcoma) diseases. To date, the...
6.
Wills R, Khoo K, Soni P, Patel I
Br J Clin Pharmacol
. 1990 Feb;
29(2):269-72.
PMID: 2306422
It has recently been shown by several investigators that the half-life (t1/2) of midazolam is prolonged (greater than 7 h) in a small proportion of the population. One group has...
7.
Nicholson R, Walker K, Bouzubar N, Wills R, Gee J, Rushmere N, et al.
Ann N Y Acad Sci
. 1990 Jan;
595:316-27.
PMID: 2142873
The endocrinological and clinical effects of an LH-RH agonist, Zoladex, and an antiestrogen, Nolvadex, in patients with advanced breast cancer are outlined and their potential in the therapy of nonmalignant...
8.
Holazo A, Choma N, Brown S, Lee L, Wills R
Antimicrob Agents Chemother
. 1989 Jun;
33(6):820-3.
PMID: 2764530
Twenty-three healthy male and female subjects received single 100-mg oral doses of rimantadine hydrochloride on two occasions in an open-label, sequential design with a 6-day washout between doses. The first...
9.
Massarella J, DeFeo T, Brown A, Lin A, Wills R
Br J Clin Pharmacol
. 1989 Jan;
27 Suppl 2:205S-209S.
PMID: 2527534
1. The influence of food on the pharmacokinetics and angiotensin-converting enzyme (ACE) inhibitory effects of oral 5 mg doses of cilazapril was investigated in a two-way crossover study in 16...
10.
Tominack R, Wills R, Gustavson L, Hayden F
Antimicrob Agents Chemother
. 1988 Dec;
32(12):1813-9.
PMID: 3245694
To assess the possible effect of aging on rimantadine hydrochloride pharmacokinetics, single- and multiple-dose kinetics were determined in 18 healthy adults with ages between 51 and 79 years. Subjects ingested...