R J Linhardt
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Explore the profile of R J Linhardt including associated specialties, affiliations and a list of published articles.
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207
Citations
4285
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Recent Articles
1.
Wang L, Ruan Z, Wu Z, Yu Q, Chen F, Zhang X, et al.
Poult Sci
. 2021 Mar;
100(3):100965.
PMID: 33652534
We studied the correlations between egg geometrical parameters (i.e., egg shape index, sphericity, geometric mean diameter, surface area, and volume) and eggshell qualities, or the organic matrix in eggshell. Eggs...
2.
Datta P, Fu L, He W, Koffas M, Dordick J, Linhardt R
Appl Microbiol Biotechnol
. 2020 Jul;
104(16):7067-7078.
PMID: 32601738
The synthesis of sulfated polysaccharides involves the sulfation of simpler polysaccharide substrates, through the action sulfotransferases using the cofactor, 3'-phosphoadenosine-5'-phosphosulfate (PAPS). Three enzymes are essential for the in vitro synthesis...
3.
LaRiviere W, Liao S, McMurtry S, Oshima K, Han X, Zhang F, et al.
Am J Physiol Lung Cell Mol Physiol
. 2020 Apr;
318(6):L1198-L1210.
PMID: 32320623
The pulmonary epithelial glycocalyx, an anionic cell surface layer enriched in glycosaminoglycans such as heparan sulfate and chondroitin sulfate, contributes to the alveolar barrier. Direct injury to the pulmonary epithelium...
4.
Liu X, Krishnamoorthy D, Lin L, Xue P, Zhang F, Chi L, et al.
Eur Cell Mater
. 2018 Feb;
35:117-131.
PMID: 29469163
Intervertebral disc (IVD) degeneration results in the depletion of proteoglycans and glycosaminoglycans (GAGs), which can lead to structural and mechanical loss of IVD function, ingrowth of nociceptive nerve fibres and...
5.
Liu Z, Song L, Zhang F, He W, Linhardt R
Poult Sci
. 2017 Sep;
96(10):3775-3784.
PMID: 28938773
The organic matrix from normal and pimpled calcified chicken eggshells were dissociated into acid-insoluble, water-insoluble, and facultative-soluble (both acid- and water-soluble) components, to understand the influence of shell matrix on...
6.
Liu Z, Sun X, Cai C, He W, Zhang F, Linhardt R
Poult Sci
. 2016 Jun;
95(12):2879-2888.
PMID: 27287383
Glycosaminoglycans (GAG) are linear, highly negatively charged polysaccharides that may perform an important role in biomineralization. GAG were isolated from chicken eggshell membranes and calcified shells. Disaccharide compositional analysis was...
7.
Zhang J, Suflita M, Fiaschetti C, Li G, Li L, Zhang F, et al.
J Appl Microbiol
. 2014 Nov;
118(1):92-8.
PMID: 25362996
Aims: One of six heparin biosynthetic enzymes, cloned and expressed in Escherichia coli as a soluble fusion protein, requires large-scale preparation for use in the chemoenzymatic synthesis of heparin, an...
8.
Maeda N, Miao J, Simmons T, Dordick J, Linhardt R
Carbohydr Polym
. 2014 Feb;
102:950-5.
PMID: 24507368
Composite polysaccharide fibers composed two oppositely charged natural polysaccharides, chitosan and hyaluronic acid, were prepared by electrospinning and subsequent coating. The fiber size distribution was characterized by scanning electron microscopy....
9.
Lamb D, Wang H, Mallis L, Linhardt R
J Am Soc Mass Spectrom
. 2013 Nov;
3(8):797-803.
PMID: 24234702
Negative ion fast-atom bombardment tandem mass spectrometry has been used in the analysis of monosulfated. disaccharides. These commercially obtained disaccharides have been enzymatically prepared from glycosaminoglycans using polysaccharide lyases. Three...
10.
Park Y, Hong Y, Weyers A, Kim Y, Linhardt R
IET Nanobiotechnol
. 2011 Sep;
5(3):69-78.
PMID: 21913788
Currently, sustainability initiatives that use green chemistry to improve and/or protect our global environment are becoming focal issues in many fields of research. Instead of using toxic chemicals for the...