R J Francis
Overview
Explore the profile of R J Francis including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
516
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Recent Articles
1.
Parry R, Wright K, Bellinge J, Ebert M, Rowshanfarzad P, Francis R, et al.
Int J Cardiovasc Imaging
. 2024 Jul;
40(9):1847-1861.
PMID: 38967895
To evaluate a convolutional neural network's performance (nnU-Net) in the assessment of vascular contours, calcification and PET tracer activity using Ga-68 DOTATATE PET/CT. Patients who underwent Ga-68 DOTATATE PET/CT imaging...
2.
Nowak A, Cook A, McDonnell A, Millward M, Creaney J, Francis R, et al.
Ann Oncol
. 2015 Sep;
26(12):2483-90.
PMID: 26386124
Background: Data from murine models suggest that CD40 activation may synergize with cytotoxic chemotherapy. We aimed to determine the maximum tolerated dose (MTD) and toxicity profile and to explore immunological...
3.
Francis R, Butler R, Stewart G
Cell Death Dis
. 2014 Oct;
5:e1474.
PMID: 25321481
Mycobacterium tuberculosis infection generates pulmonary granulomas that consist of a caseous, necrotic core surrounded by an ordered arrangement of macrophages, neutrophils and T cells. This inflammatory pathology is essential for...
4.
Teh R, Feeney K, Francis R, Phillips M, Millward M
Intern Med J
. 2013 Dec;
43(12):1342-6.
PMID: 24330366
We present three patients with lung nodules with an antecedent history of primary cutaneous melanoma or metastasis of melanoma to extrathoracic lymph nodes. Based on radiological findings, it was suspected...
5.
Dunwell J, Francis R, Powell W
Theor Appl Genet
. 2013 Nov;
74(1):60-4.
PMID: 24241457
The inheritance of the ability of barley anthers to produce microspore-derived callus in vitro was investigated. The genotypes selected were the two spring cultivars 'Dissa' (D) and 'Sabarlis' (S), the...
6.
Francis R, Kotecha S, Hallett M
J Leukoc Biol
. 2012 Oct;
93(1):95-100.
PMID: 23089743
Physiologically, apoptotic neutrophils are ingested before they undergo necrosis. However, failure of ingestion will lead to necrosis of neutrophils and the unregulated release of neutrophil-derived pathogenic molecules, such as protease...
7.
Boucek J, Francis R, Jones C, Khan N, Turlach B, Green A
Phys Med Biol
. 2008 Jul;
53(16):4213-30.
PMID: 18653927
SUVmax is currently the most common semi-quantitative method of response assessment on FDG PET. By defining the tumour volume of interest (VOI), a measure of total glycolytic volume (TGV) may...
8.
Semiautomatic volume of interest drawing for (18)F-FDG image analysis-method and preliminary results
Green A, Francis R, Baig S, Begent R
Eur J Nucl Med Mol Imaging
. 2007 Oct;
35(2):393-406.
PMID: 17909793
Purpose: Functional imaging of cancer adds important information to the conventional measurements in monitoring response. Serial (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET), which indicates changes in glucose metabolism in tumours,...
9.
Francis R, Mather S, Chester K, Sharma S, Bhatia J, Pedley R, et al.
Eur J Nucl Med Mol Imaging
. 2004 Mar;
31(8):1090-6.
PMID: 15029458
MFECP1 is a glycosylated recombinant fusion protein composed of MFE-23, a high-affinity anti-carcinoembryonic antigen (CEA) single chain Fv (scFv), fused to the enzyme carboxypeptidase G2 (CPG2), and has been constructed...
10.
Francis R, Sharma S, Springer C, Green A, Sena L, Martin J, et al.
Br J Cancer
. 2002 Sep;
87(6):600-7.
PMID: 12237768
Antibody-directed enzyme prodrug therapy is a targeted therapy in which a prodrug is activated selectively at the tumour site by an enzyme, which has been targeted to the tumour by...