R J Barsotti
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Explore the profile of R J Barsotti including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
303
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Recent Articles
1.
Regnier M, Martin H, Barsotti R, Rivera A, Martyn D, Clemmens E
Biophys J
. 2004 Sep;
87(3):1815-24.
PMID: 15345560
In striated muscle thin filament activation is initiated by Ca(2+) binding to troponin C and augmented by strong myosin binding to actin (cross-bridge formation). Several lines of evidence have led...
2.
Barsotti R
J Pediatr
. 2001 Jan;
138(1 Suppl):S11-9;discussion S19-20.
PMID: 11148545
The measurement of ammonia, now known to be a normal constituent of all body fluids, is fraught with problems. An elevated ammonia level in blood (100 micromol/L or higher) is...
3.
Spencer C, Barsotti R, Berlin J
J Mol Cell Cardiol
. 2000 Jun;
32(7):1285-300.
PMID: 10860770
Previous work suggests that strontium ions (Sr(2+)) are less effective than calcium ions (Ca(2+)) at supporting excitation-contraction (EC) coupling in cardiac muscle. We therefore tested whether this was due to...
4.
Dantzig J, Barsotti R, Manz S, Sweeney H, Goldman Y
Biophys J
. 1999 Jul;
77(1):386-97.
PMID: 10388765
When smooth muscle myosin subfragment 1 (S1) is bound to actin filaments in vitro, the light chain domain tilts upon release of MgADP, producing a approximately 3.5-nm axial motion of...
5.
Barsotti R, Dantzig J, Goldman Y
Nat Struct Biol
. 1996 Sep;
3(9):737-9.
PMID: 8784343
No abstract available.
6.
LaBelle E, Fulbright R, Barsotti R, Gu H, Polyak E
Am J Physiol
. 1996 Mar;
270(3 Pt 2):H1031-7.
PMID: 8780200
We assessed the sensitivity of phospholipase D (PLD) activity in vascular smooth muscle to cytosolic Ca2+ by increasing cytosolic Ca2+ levels independently of agonist stimulation. When rat tail artery was...
7.
Kaplan J, Barsotti R
Biophys J
. 1996 Feb;
70(2):1006-16.
PMID: 8789118
Nitrophenyl-EGTA and DM-nitrophen are Ca2+ cages that release Ca2+ when cleaved upon illumination with near-ultraviolet light. Laser photolysis of nitrophenyl-EGTA produced transient intermediates that decayed biexponentially with rates of 500,000...
8.
Martin H, Barsotti R
Biophys J
. 1994 Nov;
67(5):1933-41.
PMID: 7858130
The kinetics of force production in chemically skinned trabeculae from the guinea pig were studied by laser photolysis of caged ATP in the presence of Ca2+. Preincubation of the tissue...
9.
Martin H, Barsotti R
Biophys J
. 1994 Apr;
66(4):1115-28.
PMID: 8038383
The kinetics of ATP-induced rigor cross-bridge detachment were studied by initiating relaxation in chemically skinned trabeculae of the guinea pig heart using photolytic release of ATP in the absence of...
10.
Smith J, Barsotti R
Am J Physiol
. 1993 Nov;
265(5 Pt 1):C1424-32.
PMID: 8238490
We have developed a computer-based servo system for controlling isotonic releases in muscle. This system is a composite of commercially available devices: an IBM personal computer, an analog-to-digital (A/D) board,...