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R I Holt

Explore the profile of R I Holt including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 83
Followers 0
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Recent Articles
1.
Holt R, Webb E, Pentecost C, Sonksen P
J Clin Endocrinol Metab . 2001 Dec; 86(12):5715-20. PMID: 11739427
Exercise is a potent stimulus for GH secretion. Aging and obesity are associated with a diminution of GH secretion. We wanted to determine whether age or fat mass is more...
2.
Holt R, Miklaszewicz P, Cranston I, Russell-Jones D, Rees P, Sonksen P
Clin Endocrinol (Oxf) . 2001 Oct; 55(4):537-42. PMID: 11678838
Objectives: Computers are a part of everyday life and offer an exciting way of learning. The aim of our study was to determine the effectiveness of teaching undergraduate endocrinology using...
3.
Holt R, Powrie J, Sonksen P
J R Soc Med . 2001 Feb; 93(12):636-8. PMID: 11193062
No abstract available.
4.
Holt R, Teale J, Jones J, Quin J, McGregor A, Miell J
Growth Horm IGF Res . 2000 Sep; 8(6):447-54. PMID: 10985756
We describe a case of non-islet cell tumour hypoglycaemia (NICTH) associated with a renal cell carcinoma. Serum insulin-like growth factors (IGFs) (including IGF-II E peptide), IGF-binding proteins (IGFBPs), insulin and...
5.
Holt R, Miell J, Jones J, Mieli-Vergani G, Baker A
Clin Endocrinol (Oxf) . 2000 Feb; 52(2):217-24. PMID: 10671950
Objective: Complications of childhood cirrhosis include abnormal growth and malnutrition, associated with abnormalities in circulating IGFs and IGFBPs. Controlled studies suggest that intensive enteral feeding enhances nutritional status. The aim...
6.
Bramkamp G, Holt R, Bending J, Umasankar R, COOKE R
Int J STD AIDS . 1999 Dec; 10(10):687-8. PMID: 10582640
No abstract available.
7.
Holt R, Jones J, Baker A, Buchanan C, Miell J
J Clin Endocrinol Metab . 1999 Sep; 84(9):3277-82. PMID: 10487699
Chronic liver disease is associated with GH resistance, which is characterized by high circulating GH and low insulin-like growth factor I (IGF-I) concentrations. Standard GH replacement has no effect on...
8.
Holt R, Baker A, Jones J, Miell J
Pediatr Transplant . 1999 Mar; 2(1):76-84. PMID: 10084765
Over 50% of children with established cirrhosis have evidence of growth failure and malnutrition. Orthotopic liver transplantation (OLT) is a successful treatment for many children and leads to improved growth...
9.
Shen X, Holt R, Miell J, Justice S, Portmann B, Postel-Vinay M, et al.
J Clin Endocrinol Metab . 1998 Jul; 83(7):2532-8. PMID: 9661639
In cirrhosis, as in other conditions of protein catabolism, there is a state of acquired GH resistance, as defined by high circulating GH levels with low insulin-like growth factor I...
10.
Roberts G, Holt R, Ghatei M, Baker A, Bloom S, Miell J
Clin Endocrinol (Oxf) . 1998 Jun; 48(4):401-6. PMID: 9640405
Objective: Leptin, the product of the ob gene, is a postulated feedback regulator of adiposity with appetite suppressant and catabolic effects. Catabolic states are associated with decreased body fat mass...