R H Wiltrout
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Explore the profile of R H Wiltrout including associated specialties, affiliations and a list of published articles.
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123
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1818
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Recent Articles
11.
Akiyama Y, Watanabe M, Maruyama K, Ruscetti F, Wiltrout R, Yamaguchi K
Gene Ther
. 2001 Feb;
7(24):2113-21.
PMID: 11223993
Dendritic cells (DC) that have been genetically modified to express cytokine genes may be novel tools for inducing antitumor immune responses. In the present study, the pMX retroviral vector was...
12.
Welniak L, Khaled A, Anver M, Komschlies K, Wiltrout R, Durum S, et al.
J Immunol
. 2001 Feb;
166(5):2924-8.
PMID: 11207240
IL-7 is a critical cytokine in the development of T and B cells but little is known about its activity on nonhematopoietic cells. An unexpected finding was noted in allogeneic...
13.
Wigginton J, Park J, Gruys M, Young H, Jorcyk C, Back T, et al.
J Immunol
. 2001 Jan;
166(2):1156-68.
PMID: 11145697
Using a novel transgenic mouse model of spontaneous mammary carcinoma, we show here that the IL-12/pulse IL-2 combination can induce rapid and complete regression of well-established autochthonous tumor in a...
14.
Welniak L, Blazar B, Anver M, Wiltrout R, Murphy W
Biol Blood Marrow Transplant
. 2000 Dec;
6(6):604-12.
PMID: 11128810
Although alloreactive T cells are required for the induction of graft-versus-host disease (GVHD), other factors can influence outcome in murine models of the disease. Lethal total body irradiation (TBI) conditioning...
15.
Hoshino T, Yagita H, Ortaldo J, Wiltrout R, Young H
Eur J Immunol
. 2000 Aug;
30(7):1998-2006.
PMID: 10940889
IL-18 is considered to be a strong cofactor for CD4+ T helper 1 (Th1) cell induction. We have recently reported that IL-18 can induce IL-13 production in both NK cells...
16.
Wiltrout R
Immunol Rev
. 2000 May;
174:63-76.
PMID: 10807507
The liver is a complex organ composed of hepatic parenchymal cells and a variety of non-parenchymal cells that consist of endothelial cells, Kupffer cells, and several subsets of resident lymphocytes,...
17.
Lee J, Sayers T, Brooks A, Back T, Young H, Komschlies K, et al.
J Immunol
. 1999 Dec;
164(1):231-9.
PMID: 10605016
The role of Fas in the regulation of solid tumor growth was investigated. Murine renal carcinoma (Renca) cells were constitutively resistant to Fas-mediated killing in vitro, but exhibited increased expression...
18.
Ito D, Back T, Shakhov A, Wiltrout R, Nedospasov S
J Immunol
. 1999 Aug;
163(5):2809-15.
PMID: 10453025
Mice deficient in lymphotoxin (LT)-alpha lack peripheral lymph nodes and Peyer's patches and have profound defects in development of follicular dendritic cell networks, germinal center formation, and T/B cell segregation...
19.
Watanabe M, Fenton R, Wigginton J, McCORMICK K, Volker K, Fogler W, et al.
J Immunol
. 1999 Aug;
163(4):1943-50.
PMID: 10438930
In this study four murine IL-12 naked DNA expression plasmids (pIL-12), containing both the p35 and p40 subunits, were shown to induce systemic biological effects in vivo after intradermal injection....
20.
Hoshino T, Wiltrout R, Young H
J Immunol
. 1999 May;
162(9):5070-7.
PMID: 10227975
IL-13 and IL-4 have similar biological activities and are characteristic of cytokines expressed by Th2 cells. In contrast, IL-12 and IL-18 have been shown to be strong cofactors for Th1...