J R Ortaldo
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Explore the profile of J R Ortaldo including associated specialties, affiliations and a list of published articles.
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219
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4614
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Recent Articles
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Watte C, Nakamura T, Lau C, Ortaldo J, Stein-Streilein J
J Leukoc Biol
. 2008 Jan;
83(4):928-35.
PMID: 18192489
Similar to their activity on NK cells, Ly49 molecules play a pivotal role in influencing how NKT cells respond. It is known that Ly49 C/I is an inhibitory receptor capable...
3.
Blanca I, Bere E, Young H, Ortaldo J
J Immunol
. 2001 Nov;
167(11):6132-9.
PMID: 11714772
NK cells are a subpopulation of lymphocytes characterized primarily by their cytolytic activity. They are recognized as an important component of the immune response against virus infection and tumors. In...
4.
Anderson S, Ortaldo J, McVicar D
Immunol Rev
. 2001 Aug;
181:79-89.
PMID: 11513154
The mouse lectin-related Ly49 family and the human killer cell Ig-like receptor (KIR) family represent structurally distinct, yet functionally analogous, class I MHC receptors that are expressed on natural killer...
5.
Makrigiannis A, Pau A, Saleh A, Ortaldo J, Anderson S
J Immunol
. 2001 Apr;
166(8):5034-43.
PMID: 11290784
The Ly49 family of NK cell receptors and its MHC-binding characteristics have only been well characterized in C57BL/6 (B6) mice. Previous studies have shown that 129/J mice express unique Ly49...
6.
Ortaldo J, Bere E, Hodge D, Young H
J Immunol
. 2001 Apr;
166(8):4994-9.
PMID: 11290779
In an attempt to understand potential novel functions of receptors in vivo, we evaluated gene expression after cross-linking the activating Ly-49D mouse NK receptor. Gene expression was evaluated using a...
7.
Makrigiannis A, Etzler J, Mason A, Ortaldo J, Anderson S
J Leukoc Biol
. 2000 Nov;
68(5):765-71.
PMID: 11073118
Previous studies have indicated that NK cells from different strains of inbred mice may express distinct Ly49 repertoires. Screening of NK cells from the CBA/J mouse for inhibitory and activating...
8.
Ortaldo J, Wiegand G
J Leukoc Biol
. 2000 Nov;
68(5):748-56.
PMID: 11073116
Developmental changes in the repertoire of activating Ly-49 family members have not been examined previously. In the present study, we have examined the expression and function of the activating Ly-49s...
9.
Hoshino T, Yagita H, Ortaldo J, Wiltrout R, Young H
Eur J Immunol
. 2000 Aug;
30(7):1998-2006.
PMID: 10940889
IL-18 is considered to be a strong cofactor for CD4+ T helper 1 (Th1) cell induction. We have recently reported that IL-18 can induce IL-13 production in both NK cells...
10.
Peacock C, Lin M, Ortaldo J, Welsh R
J Virol
. 2000 Jul;
74(15):7032-8.
PMID: 10888642
The role of negatively signaling NK cell receptors of the Ly49 family on the specificity of the acute CD8(+) cytotoxic T-lymphocyte (CTL) response was investigated in lymphocytic choriomeningitis virus (LCMV)-infected...