R H Brown Jr
Overview
Explore the profile of R H Brown Jr including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
137
Citations
7795
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ticozzi N, Vance C, Leclerc A, Keagle P, Glass J, McKenna-Yasek D, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2011 Mar;
156B(3):285-90.
PMID: 21438137
FUS, EWS, and TAF15 belong to the TET family of structurally similar DNA/RNA-binding proteins. Mutations in the FUS gene have recently been discovered as a cause of familial amyotrophic lateral...
2.
Taes I, Goris A, Lemmens R, van Es M, van den Berg L, Chio A, et al.
Neurology
. 2010 May;
74(21):1687-93.
PMID: 20498436
Background: The microtubule-associated protein tau is thought to play a pivotal role in neurodegeneration. Mutations in the tau coding gene MAPT are a cause of frontotemporal dementia, and the H1/H1...
3.
Collie A, Landsverk M, Ruzzo E, Mefford H, Buysse K, Adkins J, et al.
J Med Genet
. 2009 Nov;
47(9):601-7.
PMID: 19939853
Background: Genomic copy number variants have been shown to be responsible for multiple genetic diseases. Recently, a duplication in septin 9 (SEPT9) was shown to be causal for hereditary neuralgic...
4.
Ticozzi N, Silani V, Leclerc A, Keagle P, Gellera C, Ratti A, et al.
Neurology
. 2009 Sep;
73(15):1180-5.
PMID: 19741215
Objective: Mutations in the FUS gene on chromosome 16 have been recently discovered as a cause of familial amyotrophic lateral sclerosis (FALS). This study determined the frequency and identities of...
5.
Wills A, Cronin S, Slowik A, Kasperaviciute D, van Es M, Morahan J, et al.
Neurology
. 2009 Mar;
73(1):16-24.
PMID: 19321847
Background: Six candidate gene studies report a genetic association of DNA variants within the paraoxonase locus with sporadic amyotrophic lateral sclerosis (ALS). However, several other large studies, including five genome-wide...
6.
Kwiatkowski Jr T, Bosco D, Leclerc A, Tamrazian E, Vanderburg C, Russ C, et al.
Science
. 2009 Mar;
323(5918):1205-8.
PMID: 19251627
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disorder. Ten percent of cases are inherited; most involve unidentified genes. We report here 13 mutations in the fused in...
7.
Wills A, Landers J, Zhang H, Richter R, Caraganis A, Cudkowicz M, et al.
Neurology
. 2008 Mar;
70(12):929-34.
PMID: 18347314
Objective: Four recent studies report a genetic association of the paraoxonase locus with sporadic amyotrophic lateral sclerosis (ALS). We tested the hypothesis that this association correlates with functional changes in...
8.
Landers J, Leclerc A, Shi L, Virkud A, Cho T, MAXWELL M, et al.
Neurology
. 2008 Mar;
70(14):1179-85.
PMID: 18322265
Objective: Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disorder involving upper and lower motor neurons. The vesicle-associated membrane protein B (VAPB) gene has been genetically linked to ALS in...
9.
McCormick A, Brown Jr R, Cudkowicz M, Al-Chalabi A, Garson J
Neurology
. 2008 Jan;
70(4):278-83.
PMID: 18209202
Background: Retroviral involvement in amyotrophic lateral sclerosis (ALS) has been suspected for several years since the recognition that both murine and human retroviruses can cause ALS-like syndromes. Nonquantitative studies have...
10.
Broom W, Johnson D, Auwarter K, Iafrate A, Russ C, Al-Chalabi A, et al.
Neurosci Lett
. 2007 Dec;
430(3):241-5.
PMID: 18055113
Familial amyotrophic lateral sclerosis (ALS) accounts for 10% of all ALS. Approximately 20% of cases are due to mutations in the Cu/Zn superoxide dismutase gene (SOD1). In North America, SOD1(A4V)...