R Frigg
Overview
Explore the profile of R Frigg including associated specialties, affiliations and a list of published articles.
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34
Citations
530
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Recent Articles
1.
Frigg R, Wenzel A, Grimm C, Reme C
Ophthalmologe
. 2005 Jul;
102(8):757-63.
PMID: 15990984
Hereditary retinal degeneration is characterized by apoptotic photoreceptor loss, a process governed by intricate molecular interplay and initiated when proapoptotic signals predominate in the individual cell. Identification of molecules involved...
2.
Frigg R, Ulrich D
Ther Umsch
. 2004 Feb;
60(12):723-8.
PMID: 14753150
Biological osteosynthesis is a new paradigm in fracture fixation. In contrast to the conservative mechanical operative period, where exact anatomical and rigid fracture fixation was the ultimate ambition, the new...
3.
Frigg R, Appenzeller A, Christensen R, Frenk A, Gilbert S, Schavan R
Injury
. 2002 Mar;
32 Suppl 3:SC24-31.
PMID: 11888191
Fractures around the knee typically require operative fixation to achieve an acceptable, functional outcome. The idea behind the Less Invasive Stabilization System (LISS) was to combine the advantages of both...
4.
Raeber A, Montrasio F, Hegyi I, Frigg R, Klein M, Aguzzi A, et al.
Dev Immunol
. 2002 Jan;
8(3-4):291-304.
PMID: 11785678
Some of the early events following scrapie infection take place in the lymphoreticular system (LRS) and result in significant replication of prions in lymphoid organs. The identity of the cells...
5.
Frigg R
Injury
. 2001 Nov;
32 Suppl 2:63-6.
PMID: 11718740
Based on many years of experience with compression plating and promising results obtained with so-called internal fixators, an implant system was developed which combines the two treatment methods in one...
6.
Delloca A, Tepic S, Frigg R, Meisser A, Haas N, Perren S
Clin Orthop Relat Res
. 2001 Aug;
(389):196-205.
PMID: 11501811
Some major complications of internal fixation with plates, such as infections and disturbance of healing, have been shown to be related to necrosis of bone and to the soft tissues...
7.
Weissmann C, Raeber A, Montrasio F, Hegyi I, Frigg R, Klein M, et al.
Philos Trans R Soc Lond B Biol Sci
. 2001 Mar;
356(1406):177-84.
PMID: 11260798
Following intracerebral or peripheral inoculation of mice with scrapie prions, infectivity accumulates first in the spleen and only later in the brain. In the spleen of scrapie-infected mice, prions were...
8.
Brandner S, Klein M, Frigg R, Pekarik V, Parizek P, Raeber A, et al.
Exp Physiol
. 2001 Feb;
85(6):705-12.
PMID: 11187965
The prion was defined by Stanley B. Prusiner as the infectious agent that causes transmissible spongiform encephalopathies. A pathological protein accumulating in the brain of scrapie-infected hamsters was isolated in...
9.
Montrasio F, Frigg R, Glatzel M, Klein M, Mackay F, Aguzzi A, et al.
Science
. 2000 May;
288(5469):1257-9.
PMID: 10818004
In scrapie-infected mice, prions are found associated with splenic but not circulating B and T lymphocytes and in the stroma, which contains follicular dendritic cells (FDCs). Formation and maintenance of...
10.
Frigg R, Klein M, Hegyi I, Zinkernagel R, Aguzzi A
J Virol
. 1999 Oct;
73(11):9584-8.
PMID: 10516067
Prion infections can present without clinical manifestations. B-cell deficiency may be a model for subclinical transmissible spongiform encephalopathy, since it protects mice from disease upon intraperitoneal administration of scrapie prions;...