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C Weissmann

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Articles 228
Citations 10486
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Recent Articles
1.
Flechsig E, Weissmann C
Curr Mol Med . 2004 Sep; 4(4):337-53. PMID: 15354865
Transmissible spongiform encephalopathies (TSEs) such as scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt-Jacob disease (CJD) and Gerstmann-Sträussler-Scheinker syndrome (GSS) in humans, are caused by an infectious...
2.
Farina M, Ribeiro M, Weissmann C, Estevez A, Billi S, Vercelli C, et al.
J Steroid Biochem Mol Biol . 2004 Sep; 91(4-5):211-8. PMID: 15336698
Myometrial quiescence is a key factor in all species to accomplish a successful gestation. PGs play a crucial role in mediating parturition events, and their synthesis and metabolism are regulated...
3.
Tabrizi S, Elliott C, Weissmann C
Br Med Bull . 2003 Oct; 66:305-16. PMID: 14522867
Prion diseases or transmissible spongiform encephalopathies are a group of closely related transmissible neurodegenerative conditions of humans and animals, all of which are incurable. In recent years, they have captured...
4.
Weissmann C, Flechsig E
Br Med Bull . 2003 Oct; 66:43-60. PMID: 14522848
Spongiform encephalopathies such as scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt-Jacob disease (CJD) and Gerstmann-Sträussler-Scheinker syndrome (GSS) in humans is caused by a transmissible agent designated...
5.
Klohn P, Stoltze L, Flechsig E, Enari M, Weissmann C
Proc Natl Acad Sci U S A . 2003 Sep; 100(20):11666-71. PMID: 14504404
Prions are usually quantified by bioassays based on intracerebral inoculation of mice that are slow, imprecise, and costly. We have isolated neuroblastoma N2a sublines highly susceptible to mouse prions, as...
6.
Weissmann C, Enari M, Klohn P, Rossi D, Flechsig E
J Infect Dis . 2002 Nov; 186 Suppl 2:S157-65. PMID: 12424692
The "protein only" hypothesis holds that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein that is predominantly expressed in the brain. This...
7.
Weissmann C, Enari M, Klohn P, Rossi D, Flechsig E
Proc Natl Acad Sci U S A . 2002 Aug; 99 Suppl 4:16378-83. PMID: 12181490
The "protein only" hypothesis states that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein predominantly expressed in brain, and is strongly supported...
8.
Raeber A, Montrasio F, Hegyi I, Frigg R, Klein M, Aguzzi A, et al.
Dev Immunol . 2002 Jan; 8(3-4):291-304. PMID: 11785678
Some of the early events following scrapie infection take place in the lymphoreticular system (LRS) and result in significant replication of prions in lymphoid organs. The identity of the cells...
9.
Flechsig E, Hegyi I, Enari M, Schwarz P, Collinge J, Weissmann C
Mol Med . 2001 Nov; 7(10):679-84. PMID: 11713367
Background: Prions are unusually resistant to conventional disinfection procedures. An electrode used intracerebrally on a Creutzfeldt-Jakob disease (CJD) patient transmitted the disease to two patients in succession and finally to...
10.
Enari M, Flechsig E, Weissmann C
Proc Natl Acad Sci U S A . 2001 Jul; 98(16):9295-9. PMID: 11470893
Exposure of susceptible neuroblastoma N2a cells to mouse scrapie prions leads to infection, as evidenced by the continued presence of the scrapie form of the prion protein (PrP(Sc)) and infectivity...