R Fettiplace
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Explore the profile of R Fettiplace including associated specialties, affiliations and a list of published articles.
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53
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2544
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Recent Articles
1.
Fettiplace R, Andrews D, Haydon D
J Membr Biol
. 2013 Nov;
5(3):277-96.
PMID: 24173132
It has been shown that the capacitance, thickness and composition of black lipid films may depend strongly on the hydrocarbon solvent used in their formation. By the use of n-hexadecane,...
2.
Ashmore J, Avan P, Brownell W, Dallos P, Dierkes K, Fettiplace R, et al.
Hear Res
. 2010 Jun;
266(1-2):1-17.
PMID: 20541061
This composite article is intended to give the experts in the field of cochlear mechanics an opportunity to voice their personal opinion on the one mechanism they believe dominates cochlear...
3.
Kennedy H, Crawford A, Fettiplace R
Nature
. 2005 Feb;
433(7028):880-3.
PMID: 15696193
It is generally accepted that the acute sensitivity and frequency discrimination of mammalian hearing requires active mechanical amplification of the sound stimulus within the cochlea. The prevailing hypothesis is that...
4.
Ricci A, Crawford A, Fettiplace R
J Neurosci
. 2002 Jan;
22(1):44-52.
PMID: 11756487
Sound stimuli vibrate the hair bundles on auditory hair cells, but the resulting motion attributable to the mechanical stimulus may be modified by forces intrinsic to the bundle, which drive...
5.
Fettiplace R, Ricci A, Hackney C
Trends Neurosci
. 2001 Feb;
24(3):169-75.
PMID: 11182457
Sound stimuli are detected in the cochlea by vibration of hair bundles on sensory hair cells, which activates mechanotransducer ion channels and generates an electrical signal. Remarkably, the process can...
6.
Ricci A, Crawford A, Fettiplace R
J Neurosci
. 2000 Sep;
20(19):7131-42.
PMID: 11007868
During transduction in auditory hair cells, hair bundle deflection opens mechanotransducer channels that subsequently reclose or adapt to maintained stimuli, a major component of the adaptation occurring on a submillisecond...
7.
Ricci A, Fettiplace R
J Physiol
. 2000 Apr;
524 Pt 2:423-36.
PMID: 10766923
Turtle cochlear hair cells are electrically tuned by a voltage-dependent Ca2+ current and a Ca2+-dependent K+ current (IBK(Ca)). The effects of intracellular calcium buffering on electrical tuning were studied in...
8.
Wu Y, Ricci A, Fettiplace R
J Neurophysiol
. 1999 Nov;
82(5):2171-81.
PMID: 10561397
Mechanoelectrical transducer currents in turtle auditory hair cells adapted to maintained stimuli via a Ca(2+)-dependent mechanism characterized by two time constants of approximately 1 and 15 ms. The time course...
9.
Jones E, Fettiplace R
J Physiol
. 1999 Jul;
518 ( Pt 3):653-65.
PMID: 10420004
1. Turtle auditory hair cells contain multiple isoforms of the pore-forming alpha-subunit of the large-conductance Ca2+-activated K+ (KCa) channel due to alternative splicing at two sites. Six splice variants were...
10.
Jones E, Art J, Fettiplace R
Ann N Y Acad Sci
. 1999 Jul;
868:379-85.
PMID: 10414307
Turtle auditory hair cells are frequency tuned by the activity of large-conductance calcium-activated potassium (KCa) channels, the frequency range being dictated primarily by the channel kinetics. Seven alternatively spliced isoforms...