R Fernandez-Botran
Overview
Explore the profile of R Fernandez-Botran including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
743
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0
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Recent Articles
1.
Vetvicka V, Fernandez-Botran R
Helminthologia
. 2019 Oct;
55(3):177-184.
PMID: 31662645
Immunosuppression caused by parasitic infections represents the foremost way by which the parasites overcome or escape the host's immune response. Glucan is a well-established natural immunomodulator with the ability to...
2.
Bordon J, Fernandez-Botran R, Wiemken T, Peyrani P, Uriarte S, Arnold F, et al.
Infection
. 2015 Oct;
43(6):729-38.
PMID: 26424683
Purpose: Further examination of clinical outcomes and inflammatory response of bacteremic pneumococcal community-acquired pneumonia (CAP) is of great interest to enhance the care of patients with pneumococcal CAP. Methods: This...
3.
Bordon J, Uriarte S, Arnold F, Fernandez-Botran R, Rane M, Peyrani P, et al.
Infection
. 2013 Apr;
41(5):1021-4.
PMID: 23589279
This case report shows a striking correlation of remarkable brief high levels of pro- and anti-inflammatory cytokines coupled with increased neutrophil activation, followed by a sharp decrease in cytokine levels...
4.
Fernandez-Botran R, Romanovskis P, Sun X, Spatola A
J Pept Res
. 2004 Mar;
63(2):56-62.
PMID: 15009526
Glycosaminoglycans (GAGs) play an important role in inflammatory responses due to their ability to interact with cytokines and chemokines, resulting in the localization of these mediators to specific anatomical sites,...
5.
Fernandez-Botran R
Expert Opin Investig Drugs
. 2002 Jan;
10(7):1387-9.
PMID: 11791502
Chemokine receptors have been recognised as attractive targets for drug development. Although the notion that chemokine receptor antagonism can significantly reduce inflammation has been supported by evidence obtained with modified...
6.
Fernandez-Botran R
Expert Opin Investig Drugs
. 2000 Nov;
9(3):497-514.
PMID: 11060691
Being mediators of immune and inflammatory reactions, abnormal or excessive production of cytokines is often the main cause of the pathology in many types of disease. Targeting cytokines by means...
7.
Fernandez-Botran R, Chilton P, Hondowicz B, Vetvickova J, Yan J, Jones 3rd W, et al.
J Leukoc Biol
. 1999 Sep;
66(3):481-8.
PMID: 10496319
These studies were undertaken with the purpose of elucidating the key signals involved in the regulation of the production of soluble interleukin-4 receptors (sIL-4R) in mice during Th1 and Th2...
8.
Fernandez-Botran R
Crit Rev Clin Lab Sci
. 1999 Jul;
36(3):165-224.
PMID: 10407682
Cytokine activity is tightly regulated at multiple levels. Soluble cytokine receptors (sCR) contribute to the regulation of cytokine activity by modulating the ability of cytokines to bind their membrane receptors...
9.
Fernandez-Botran R, Yan J, Justus D
Cytokine
. 1999 May;
11(5):313-25.
PMID: 10328871
Glycosaminoglycans (GAGs) are a group of negatively charged molecules present in many tissues as components of the extracellular matrix, basement and cellular membranes. This work analysed the ability of this...
10.
Chilton P, Fernandez-Botran R
Cell Immunol
. 1997 Oct;
180(2):104-15.
PMID: 9341740
The actions of interleukin-4 (IL-4) in vivo are likely to be positively influenced by the expression of membrane IL-4 receptors (mIL-4R) on target cells and negatively by the concentration of...