R E Rhoads
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Explore the profile of R E Rhoads including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
3543
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Recent Articles
21.
Gao M, Rychlik W, Rhoads R
J Biol Chem
. 1998 Mar;
273(8):4622-8.
PMID: 9468520
Two human eukaryotic initiation factor 4E (eIF4E) genes were isolated and characterized from placental and chromosome 4-specific genomic libraries. One of the genes (EIF4E1) contained six introns, but the other...
22.
Mendez R, Kollmorgen G, White M, Rhoads R
Mol Cell Biol
. 1997 Sep;
17(9):5184-92.
PMID: 9271396
The ability of insulin to stimulate protein synthesis and cellular growth is mediated through the insulin receptor (IR), which phosphorylates Tyr residues in the insulin receptor substrate-signaling proteins (IRS-1 and...
23.
Borman A, Kirchweger R, Ziegler E, Rhoads R, Skern T, Kean K
RNA
. 1997 Feb;
3(2):186-96.
PMID: 9042945
Rhinovirus 2A and foot-and-mouth disease virus Lb proteinases stimulate the translation of uncapped messages and those carrying the rhinovirus and enterovirus Internal Ribosome Entry Segments (IRESes) by a mechanism involving...
24.
Keiper B, Rhoads R
Nucleic Acids Res
. 1997 Jan;
25(2):395-402.
PMID: 9016570
Eukaryotic cellular mRNAs contain a cap at their 5'-ends, but some viral and cellular mRNAs bypass the cap-dependent mechanism of translation initiation in favor of internal entry of ribosomes at...
25.
Lamphear B, Rhoads R
Biochemistry
. 1996 Dec;
35(49):15726-33.
PMID: 8961935
Infection of cells with picornaviruses of the rhino-, aphtho-, and enterovirus groups causes a shut-off in cap-dependent translation of cellular mRNAs but permits cap-independent viral RNA translation to proceed. This...
26.
Mendez R, Myers Jr M, White M, Rhoads R
Mol Cell Biol
. 1996 Jun;
16(6):2857-64.
PMID: 8649395
Insulin rapidly stimulates protein synthesis in a wide variety of tissues. This stimulation is associated with phosphorylation of several translational initiation and elongation factors, but little is known about the...
27.
Gan W, Rhoads R
J Biol Chem
. 1996 Jan;
271(2):623-6.
PMID: 8557663
The eIF4 group initiation factors carry out recognition of the mRNA cap, unwinding of mRNA secondary structure, and binding of mRNA to the 43 S preinitiation complex. Infection by picornaviruses...
28.
Lamphear B, Kirchweger R, Skern T, Rhoads R
J Biol Chem
. 1995 Sep;
270(37):21975-83.
PMID: 7665619
Cap-dependent binding of mRNA to the 40 S ribosomal subunit during translational initiation requires the association of eukaryotic initiation factor 4G (eIF4G; formerly eIF-4 gamma and p220) with other initiation...
29.
Joshi B, Cai A, Keiper B, Minich W, Mendez R, Beach C, et al.
J Biol Chem
. 1995 Jun;
270(24):14597-603.
PMID: 7782323
Initiation factor 4E (eIF-4E) binds to the m7GTP-containing cap of eukaryotic mRNA and facilitates the entry of mRNA into the initiation cycle of protein synthesis. eIF-4E is a phosphoprotein, and...
30.
Yan R, Rhoads R
Genomics
. 1995 Mar;
26(2):394-8.
PMID: 7601469
Messenger RNA binding to the ribosome, the rate-limiting step in eukaryotic protein synthesis, is catalyzed by the eIF-4 group of initiation factors. These factors collectively bind to the m7GTP-containing cap...