R E Alcalde
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Explore the profile of R E Alcalde including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
238
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Recent Articles
11.
Sasaki A, Kitamura K, Alcalde R, Tanaka T, Suzuki A, Etoh Y, et al.
Int J Cancer
. 1998 Jul;
77(2):279-85.
PMID: 9650565
YH529, [1-hydroxy-2-(imidazo [1,2-a] pyridin-3-yl) ethylidene]-bisphosphonic acid monohydrate, is a newly developed third-generation bisphosphonate with a potent inhibitory activity toward osteoclastic bone resorption. The primary cellular mechanism of osteolysis associated with...
12.
Alcalde R, Ueyama Y, Lim D, Matsumura T
J Oral Maxillofac Surg
. 1998 May;
56(5):676-80.
PMID: 9590353
No abstract available.
13.
Alcalde R, Jinno T, Pogrel M, Matsumura T
J Oral Maxillofac Surg
. 1998 Feb;
56(2):129-34.
PMID: 9461133
Purpose: Knowledge of the normal dentofacial patterns of adults belonging to various ethnic and age groups is important for clinical and research purposes. Lateral cephalometric standards of normal Japanese adults...
14.
Sasaki A, Alcalde R, Nishiyama A, Lim D, Mese H, Akedo H, et al.
Cancer Res
. 1998 Feb;
58(3):462-7.
PMID: 9458090
Angiogenesis inhibitor TNP-470, 6-O-(N-chloroacetyl-carbamoyl)-fumagillol, semisynthetic analogue of fumagillin, has strong inhibitory activities against in vivo tumor growth and metastasis in a wide variety of tumors. However, it is still unknown...
15.
Alcalde R, Terakado N, Otsuki K, Matsumura T
Oncology
. 1997 Jul;
54(4):324-8.
PMID: 9216858
It has been demonstrated that angiogenesis is required in the process of tumor progression and metastasis. Microvessel density (MVD) estimates tumor angiogenesis and is an independent indicator for predicting tumor...
16.
Shintani S, Alcalde R, Matsumura T, Terakado N
Cancer Lett
. 1997 Jun;
116(1):9-14.
PMID: 9177451
Adenoid cystic carcinoma (ACC) is a salivary malignant tumor with poor long-term prognosis, that is known to have predilection for invasion of the adjacent stroma and neural tissues. This carcinoma...
17.
Otsuki K, Alcalde R, Matsumura T, Kimura N
Oncology
. 1997 Jan;
54(1):63-8.
PMID: 8978595
The nm23 gene is a potential metastasis suppressor gene originally identified using a murine melanoma cell line. The nm23 proteins are nucleoside diphosphate (NDP) kinases, and there are two isotypes...
18.
Matsumura T, Yoshihama Y, Kimura T, Shintani S, Alcalde R
Oncology
. 1996 Jul;
53(4):308-12.
PMID: 8692535
The p53 tumor suppressor gene is the most commonly mutated gene in human cancer and is a frequent abnormality in oral squamous cell carcinoma and its precancerous lesions. MDM2 (murine...
19.
Alcalde R, Sasaki A, Misaki M, Matsumura T
J Oral Maxillofac Surg
. 1996 Jan;
54(1):108-11.
PMID: 8530988
No abstract available.
20.
Shintani S, Funayama T, Yoshihama Y, Alcalde R, Ootsuki K, Terakado N, et al.
Anticancer Res
. 1995 Nov;
15(6B):2623-6.
PMID: 8669836
The tyrosine kinase receptor family, including the epidermal growth factor receptor (EGF-R), c-erbB2 and, more recently, the c-erbB3, has been recognized as being of particular importance in many human malignancies....