R Drapkin
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Explore the profile of R Drapkin including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
2091
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0
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Recent Articles
1.
Xu B, Lefringhouse J, Liu Z, West D, Baldwin L, Ou C, et al.
Oncogenesis
. 2017 Jan;
6(1):e295.
PMID: 28134933
Integrins, a family of heterodimeric receptors for extracellular matrix, are promising therapeutic targets for ovarian cancer, particularly high-grade serous-type (HGSOC), as they drive tumor cell attachment, migration, proliferation and survival...
2.
Sheets J, Iwanicki M, Liu J, Howitt B, Hirsch M, Gubbels J, et al.
Oncogenesis
. 2016 Oct;
5(10):e264.
PMID: 27775699
The cause of death among the majority of epithelial ovarian cancer (EOC) patients involves passive dissemination of cancer cells within the peritoneal cavity and subsequent implantation of cancer spheroids into...
3.
Labidi-Galy S, Clauss A, Ng V, Duraisamy S, Elias K, Piao H, et al.
Oncogene
. 2014 Jan;
34(3):373-83.
PMID: 24469047
High-grade serous ovarian carcinoma (HGSOC) and basal-like breast cancer (BLBC) share many features including TP53 mutations, genomic instability and poor prognosis. We recently reported that Elafin is overexpressed by HGSOC...
4.
Dubeau L, Drapkin R
Ann Oncol
. 2013 Oct;
24 Suppl 8:viii28-viii35.
PMID: 24131966
Background: The traditional view of epithelial ovarian cancer asserts that all tumor subtypes share a common origin in the ovarian surface epithelium (OSE) DESIGN: A literature review was carried out...
5.
Levanon K, Ng V, Piao H, Zhang Y, Chang M, Roh M, et al.
Oncogene
. 2009 Nov;
29(8):1103-13.
PMID: 19935705
Recent studies suggest that some serous ovarian carcinomas (SOCs) arise from the fallopian tube (FT) epithelium rather than the ovarian surface epithelium. This hypothesis places emphasis on the FT secretory...
6.
Jarboe E, Folkins A, Drapkin R, Ince T, Agoston E, Crum C
Histopathology
. 2008 Feb;
53(2):127-38.
PMID: 18298580
Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease...
7.
Lee Y, Miron A, Drapkin R, Nucci M, Medeiros F, Saleemuddin A, et al.
J Pathol
. 2006 Nov;
211(1):26-35.
PMID: 17117391
The tubal fimbria is a common site of origin for early (tubal intraepithelial carcinoma or TIC) serous carcinomas in women with familial BRCA1 or 2 mutations (BRCA+). Somatic p53 tumour...
8.
Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, et al.
Cell
. 2001 Aug;
106(3):297-307.
PMID: 11509179
Here, we report the identification of a new E1A binding protein complex that is essential for E1A-mediated transformation. Its core component is a SWI2/SNF2-related, 400 kDa protein (p400). Other components...
9.
Cantor S, BELL D, Ganesan S, Kass E, Drapkin R, Grossman S, et al.
Cell
. 2001 Apr;
105(1):149-60.
PMID: 11301010
BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT repeats of BRCA1. A BACH1 derivative, bearing a...
10.
Vose J, Cabanillas F, OBrien S, Dang N, Drapkin R, Foss F
Oncology (Williston Park)
. 2000 Jul;
14(6 Suppl 2):41-2.
PMID: 10887644
Managing the infectious complications associated with pentostatin (Nipent), used alone or in combination with other agents in patients with low-grade lymphomas, poses a significant problem for clinicians. Since there is...