R de Castiglione
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Explore the profile of R de Castiglione including associated specialties, affiliations and a list of published articles.
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Articles
74
Citations
263
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Recent Articles
1.
Dal Pozzo A, Fagnoni M, Bergonzi R, Vanini L, de Castiglione R, Aglio C, et al.
J Pept Res
. 2000 Jul;
55(6):447-54.
PMID: 10888201
Six retro-inverso tri- and tetrapeptide analogues of RGD were prepared and their anti-aggregatory activity was determined by platelet aggregation tests in comparison with the corresponding parent peptides. An efficient method...
2.
de Castiglione R, Gozzini L
Crit Rev Oncol Hematol
. 1996 Oct;
24(2):117-51.
PMID: 8889369
No abstract available.
3.
Perego R, Gozzini L, Arlandini E, Bolis G, de Castiglione R
Int J Pept Protein Res
. 1995 Nov;
46(5):341-5.
PMID: 8567176
Endothelin-1 (ET), the most potent vasoconstrictor yet discovered, is a peptide containing 21 amino acids with two intrachain disulfide bridges. With the aim of obtaining two-chain derivatives, Et was submitted...
4.
Miasiro N, de Castiglione R, Paiva A
Eur J Pharmacol
. 1995 May;
278(2):103-9.
PMID: 7671994
The importance of residues 9 and 10 in endothelin-1 was assessed by studying the responses of the guinea-pig ileum to [Ala9]endothelin-1 and [Ala10]endothelin-1. Both analogues induced relaxation followed by contraction....
5.
Galantino M, de Castiglione R, Cristiani C, Vaghi F, Liu W, Zhang J, et al.
Pept Res
. 1995 May;
8(3):154-9.
PMID: 7670230
A systematic approach to map the functionally important determinants of endothelin-1 (ET-1) by a D-amino acid scan is described. Correct orientation of the amino acid side chains was generally of...
6.
Miasiro N, de Castiglione R, Paiva A
J Cardiovasc Pharmacol
. 1995 Jan;
26 Suppl 3:S320-1.
PMID: 8587402
The importance of residues 9 and 10 for endothelin-1 (ET-1) biologic activity was assessed by studying the responses of the guinea pig ileum to [Ala9]-ET-1 and [Ala10]-ET-1. Both analogues induced...
7.
Forino R, Galantino M, Ciprandi F, BAUMER L, Arlandini E, de Castiglione R
Int J Pept Protein Res
. 1994 Jun;
43(6):513-9.
PMID: 7928081
The impurities which formed in the large-scale synthesis of THF-gamma 2, an immunomodulatory peptide of formula H-Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu-OH, were identified by a combination of analytical methods, and their structure confirmed by...
8.
Tam J, Liu W, Zhang J, Galantino M, Bertolero F, Cristiani C, et al.
Peptides
. 1994 Jan;
15(4):703-8.
PMID: 7937349
A systematic approach to map the functional important determinants of endothelin-1 (ET) by an alanine scan is described. Studies on the in vitro receptor binding affinity and on the agonist...
9.
Ciomei M, Pastori W, PASTORI A, de Castiglione R, Gozzini L, Corradi F
Anticancer Res
. 1993 Jan;
13(1):75-9.
PMID: 8386497
Bombesin (BN) and bombesin-like peptides are autocrine growth factors for small cell lung carcinoma (SCLC). BN receptor antagonists can therefore find clinical application in the treatment of this highly malignant...
10.
de Castiglione R, Gozzini L, Galantino M, Corradi F, Ciomei M, Roletto F, et al.
Farmaco
. 1992 Jun;
47(6):855-67.
PMID: 1326977
New alkylating bombesin analogues were synthesized in order to increase their solubility and stability in aqueous solutions. The best compromise between these parameters and the biological properties (receptor binding and...