R Daniel Beauchamp
Overview
Explore the profile of R Daniel Beauchamp including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
74
Citations
2460
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Xu C, Xia P, Li J, Lewis K, Ciombor K, Wang L, et al.
Cell Rep Med
. 2024 Jul;
5(8):101661.
PMID: 39059386
Identifying patients with stage II and III colon cancer who will benefit from 5-fluorouracil (5-FU)-based adjuvant chemotherapy is crucial for the advancement of personalized cancer therapy. We employ a semi-supervised...
2.
SMAD4 Suppresses Colitis-associated Carcinoma Through Inhibition of CCL20/CCR6-mediated Inflammation
Hanna D, Marincola Smith P, Novitskiy S, Washington M, Zi J, Weaver C, et al.
Gastroenterology
. 2022 Jul;
163(5):1334-1350.e14.
PMID: 35863523
Background & Aims: We previously reported that colon epithelial cell silencing of Smad4 increased epithelial expression of inflammatory genes, including the chemokine c-c motif chemokine ligand 20 (CCL20), and increased...
3.
Szeglin B, Wu C, Marco M, Park H, Zhang Z, Zhang B, et al.
Cancer Rep (Hoboken)
. 2021 Jun;
5(1):e1423.
PMID: 34114372
Background: Colorectal cancer is the second-leading cause of cancer-related mortality in the United States and a leading cause of cancer-related mortality worldwide. Loss of SMAD4, a critical tumor suppressor and...
4.
Immunomodulatory Effects of TGF-β Family Signaling within Intestinal Epithelial Cells and Carcinomas
Marincola Smith P, Means A, Beauchamp R
Gastrointest Disord (Basel)
. 2021 Apr;
1(2):290-300.
PMID: 33834163
TGF-β superfamily signaling is responsible for many critical cellular functions including control of cell growth, cell proliferation, cell differentiation, and apoptosis. TGF-β appears to be critical in gastrulation, embryonic development,...
5.
6.
Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2021 Mar;
320(6):G936-G957.
PMID: 33759564
Defective barrier function is a predisposing factor in inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Although TGFβ signaling defects have been associated with IBD and CAC, few studies have...
7.
Shi C, Pan F, Kim J, Washington M, Padmanabhan C, Meyer C, et al.
Cell Mol Gastroenterol Hepatol
. 2019 Jul;
8(4):579-594.
PMID: 31310834
Background & Aims: Activating mutation of the KRAS gene is common in some cancers, such as pancreatic cancer, but rare in other cancers. Chronic pancreatitis is a predisposing condition for...
8.
Means A, Freeman T, Zhu J, Woodbury L, Marincola-Smith P, Wu C, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Aug;
6(3):257-276.
PMID: 30109253
Background & Aims: Chronic inflammation is a predisposing condition for colorectal cancer. Many studies to date have focused on proinflammatory signaling pathways in the colon. Understanding the mechanisms that suppress...
9.
Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson J, et al.
Dev Cell
. 2018 Mar;
44(5):566-581.e8.
PMID: 29533772
Adenomatous polyposis coli (APC) mutations cause Wnt pathway activation in human cancers. Current models for APC action emphasize its role in promoting β-catenin degradation downstream of Wnt receptors. Unexpectedly, we...
10.
Padmanabhan C, Rellinger E, Zhu J, An H, Woodbury L, Chung D, et al.
Oncotarget
. 2017 Dec;
8(60):101072-101086.
PMID: 29254146
Epithelial cancers (carcinomas) comprise the top four causes of cancer-related deaths in the United States. While overall survival has been steadily improving, therapy-resistant disease continues to present a major therapeutic...