R D McKay
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Explore the profile of R D McKay including associated specialties, affiliations and a list of published articles.
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94
Citations
5657
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Recent Articles
1.
Nikolakopoulou P, Poser S, Masjkur J, Fernandez Rubin de Celis M, Toutouna L, Andoniadou C, et al.
Horm Metab Res
. 2016 Jan;
48(2):77-82.
PMID: 26783739
The endocrine system involves communication among different tissues in distinct organs, including the pancreas and components of the Hypothalamic-Pituitary-Adrenal Axis. The molecular mechanisms underlying these complex interactions are a subject...
2.
Androutsellis-Theotokis A, Chrousos G, McKay R, DeCherney A, Kino T
Horm Metab Res
. 2012 Sep;
45(2):159-68.
PMID: 22990992
Neural stem cells (NSCs) are pluripotent precursors with the ability to proliferate and differentiate into 3 neural cell lineages, neurons, astrocytes and oligodendrocytes. Elucidation of the mechanisms underlying these biologic...
3.
Soeda A, Park M, Lee D, Mintz A, Androutsellis-Theotokis A, McKay R, et al.
Oncogene
. 2009 Sep;
28(45):3949-59.
PMID: 19718046
Hypoxia contributes to the progression of a variety of cancers by activating adaptive transcriptional programs that promote cell survival, motility and tumor angiogenesis. Although the importance of hypoxia and subsequent...
4.
Szklarczyk A, Conant K, Owens D, Ravin R, McKay R, Gerfen C
Neuroscience
. 2007 Sep;
149(1):87-98.
PMID: 17826919
Matrix metalloproteinase-7 (MMP-7) belongs to a family of zinc dependent endopeptidases that are expressed in a variety of tissues including the brain. MMPs are known to be potent mediators of...
5.
McKay R
Philos Trans R Soc Lond B Biol Sci
. 2004 Aug;
359(1445):851-6.
PMID: 15293812
The fundamental basis of our work is that organs are generated by multipotent stem cells, whose properties we must understand to control tissue assembly or repair. Central nervous system (CNS)...
6.
Panchision D, Pickel J, Studer L, Lee S, Turner P, Hazel T, et al.
Genes Dev
. 2001 Aug;
15(16):2094-110.
PMID: 11511541
Bone morphogenetic proteins (BMPs) have diverse and sometimes paradoxical effects during embryonic development. To determine the mechanisms underlying BMP actions, we analyzed the expression and function of two BMP receptors,...
7.
Sanchez-Pernaute R, Studer L, Bankiewicz K, Major E, McKay R
J Neurosci Res
. 2001 Aug;
65(4):284-8.
PMID: 11494363
The use of in vitro expanded human CNS precursors has the potential to overcome some of the ethical, logistic and technical problems of fetal tissue transplantation in Parkinson disease. Cultured...
8.
Cameron H, McKay R
J Comp Neurol
. 2001 Jun;
435(4):406-17.
PMID: 11406822
Knowing the rate of addition of new granule cells to the adult dentate gyrus is critical to understanding the function of adult neurogenesis. Despite the large number of studies of...
9.
Collin C, Vicario-Abejon C, Rubio M, Wenthold R, McKay R, Segal M
Eur J Neurosci
. 2001 Apr;
13(7):1273-82.
PMID: 11298787
We have recently demonstrated that embryonic E16 hippocampal neurons grown in cultures are unable to form fast synaptic connections unless treated with BDNF or NT-3. This experimental system offers an...
10.
Maskos U, Brustle O, McKay R
Dev Biol
. 2001 Feb;
231(1):103-12.
PMID: 11180955
The NMDA receptor, one of the two major ionotropic glutamate receptors, has been proposed to play fundamental roles in the survival, migration, differentiation, and activity-dependent maturation of neural cells. The...