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R D Krell

Explore the profile of R D Krell including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 375
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Recent Articles
1.
Galaif E, Newcomb M, Vega W, Krell R
J Drug Educ . 2007 Dec; 37(3):249-76. PMID: 18047182
A measurement model was analyzed to demonstrate a differential distribution and cumulative exposure to psychosocial risk and protective influences of adolescent drug use among ethnically-diverse adolescent samples. The sample included...
2.
Veale C, Bernstein P, Bohnert C, Brown F, Bryant C, Damewood Jr J, et al.
J Med Chem . 1997 Nov; 40(20):3173-81. PMID: 9379436
This paper describes the development a series of peptidyl trifluoromethyl ketone inhibitors of human leukocyte elastase which are found to have excellent pharmacological profiles. Methods have been developed that allow...
3.
Krell R, Dehaas C, Lengel D, Kusner E, Williams J, Buckner C
Ann N Y Acad Sci . 1994 Nov; 744:289-98. PMID: 7825851
No abstract available.
4.
Kusner E, Buckner C, Dea D, Dehaas C, Marks R, Krell R
Eur J Pharmacol . 1994 May; 257(3):285-92. PMID: 7522174
The non-redox 5-lipoxygenase inhibitor Zeneca ZD2138 (6-[(3-fluoro-5-[4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl])phenoxy- methyl]-1-methyl-2-quinolone) was evaluated for its ability to inhibit antigen-induced leukotriene release from guinea-pig lung in vitro and antigen-induced increases in pulmonary resistance in...
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Buckner C, Liberati N, Dea D, Lengel D, Campbell J, Miller S, et al.
J Pharmacol Exp Ther . 1993 Dec; 267(3):1168-75. PMID: 8263778
This study has examined the abilities of (+/-)-CP96345 and (+/-)-SR48968, nonpeptide antagonists selective for the tachykinin NK1 and NK2 receptors, respectively, to block bronchoconstriction caused by intravenous administration of direct-acting...
7.
Falcone R, Hubbs S, Vanderloo J, Prosser J, Little J, Gomes B, et al.
J Pharmacol Exp Ther . 1993 Sep; 266(3):1291-9. PMID: 8396632
Specific binding of [3H]bradykinin (BK) to guinea pig gall bladder (GPGB) membranes was protein dependent, rapid (Kon = 0.067 min-1) with high affinity (Kd = 0.45 +/- 0.02; n =...
8.
Krell R, Giles R
Agents Actions Suppl . 1993 Jan; 41:59-62. PMID: 8317342
This communication briefly summarizes the available clinical findings with several eicosanoid antagonists or synthesis inhibitors in human models of asthma.
9.
Falcone R, Krell R
J Pharmacol Exp Ther . 1992 Sep; 262(3):1095-102. PMID: 1326623
The peptide leukotrienes (LTs), LTC4, LTD4 and LTE4, produced concentration-related contraction of isolated strips of guinea pig gall bladder (GPGB) with pD2 values of 8.48 +/- 0.11, 8.26 +/- 0.22...
10.
Kusner E, Buckner C, Dehaas C, Lengel D, Marks R, Krell R
Eur J Pharmacol . 1992 Jan; 210(3):299-306. PMID: 1377129
Aerosol administration of neurokinin A (NKA) or substance P (SP) to conscious guinea pigs produced labored abdominal breathing (dyspnea). Time to onset of dyspnea was inversely related to tachykinin concentration....