L W Chakrin
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Explore the profile of L W Chakrin including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
209
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Recent Articles
1.
Regal J, Hardy T, Casey F, Chakrin L
Immunopharmacology
. 1983 Apr;
5(4):315-27.
PMID: 6189804
C5a, a product of complement system activation, causes a significant contraction of the isolated guinea pig trachea, and the antihistamine diphenhydramine does not alter the rate, amplitude, or duration of...
2.
SPICER S, Schulte B, Chakrin L
Exp Lung Res
. 1983 Feb;
4(2):137-56.
PMID: 6840046
Secretory products of epithelial cells of the human respiratory tract have been studied biochemically and by a variety of histochemical methods for differentiating and characterizing complex carbohydrates at the light...
3.
Regal J, Hardy T, Casey F, Chakrin L
Int Arch Allergy Appl Immunol
. 1983 Jan;
72(4):362-5.
PMID: 6196303
C5a has long been known to cause histamine release from isolated perfused guinea pig lung, isolated human basophils, rat and guinea pig mast cells, and guinea pig skin. The purpose...
4.
Sung C, Baker A, HOLDEN D, Smith W, Chakrin L
J Nat Prod
. 1982 Jul;
45(4):398-406.
PMID: 7130985
An aqueous extract of Angelica polymorpha was examined for its immunoregulating properties. Its effect on the production of antibodies was tested in (C57BL/6 X DBA/2)F1 mice. When the animals were...
5.
Baker A, Chakrin L, HOLDEN D, Smith W, Sung C
Int J Immunopharmacol
. 1981 Jan;
3(4):349-56.
PMID: 6460705
At least wo histamine receptors have been pharmacologically defined. Using the appropriate agonists and antagonists, the possible involvement of these receptor types in the production of reaginic antibodies in the...
6.
Weichman B, Hostelley L, Bostick S, Levi R, Chakrin L
Int Arch Allergy Appl Immunol
. 1981 Jan;
64(4):456-63.
PMID: 6162802
Immunologic histamine release was evoked from the sensitized fragmented cardiac and pulmonary tissue of the cynomolgus monkey by a reverse anaphylactic reaction. Ventricular and pulmonary tissue released a similar fraction...
7.
Weichman B, Hostelley L, Bostick S, Chakrin L
J Pharmacol Methods
. 1980 Aug;
4(1):59-69.
PMID: 6157055
No abstract available.
8.
Sung C, Baker A, Chakrin L
J Pharmacol Methods
. 1980 Jun;
3(4):277-87.
PMID: 6156365
The ability of mouse anti-dinitropheny ovalbumin (anti-DNP-OA) serum to sensitize rat lung fragments can be demonstrated by the release of histamine from the tissue after antigenic challenge. This method can...
9.
Krell R, Chakrin L
J Pharm Sci
. 1980 Feb;
69(2):239-43.
PMID: 6987373
This paper examines the advantages and disadvantages of many in vivo and in vitro experimental model systems employed in the preclinical testing of antiallergic drugs.
10.