R D Kamm
Overview
Explore the profile of R D Kamm including associated specialties, affiliations and a list of published articles.
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Articles
107
Citations
1985
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Recent Articles
1.
Boussommier-Calleja A, Atiyas Y, Haase K, Headley M, Lewis C, Kamm R
Biomaterials
. 2018 Mar;
198:180-193.
PMID: 29548546
Metastasis is the leading cause of cancer-related deaths. Recent developments in cancer immunotherapy have shown exciting therapeutic promise for metastatic patients. While most therapies target T cells, other immune cells,...
2.
Gilardi M, Bersini S, Calleja A, Kamm R, Vanoni M, Moretti M
Thromb Res
. 2016 May;
140 Suppl 1:S180-1.
PMID: 27161700
Introduction: Metastases are responsible for more than 90% of cancer related mortality. The hematogenous metastatic invasion is a complex process in which the endothelium plays a key role. Extravasation is...
3.
Pavesi A, Tan A, Chen M, Adriani G, Bertoletti A, Kamm R
Annu Int Conf IEEE Eng Med Biol Soc
. 2016 Jan;
2015:1853-6.
PMID: 26736642
Understanding the mechanism of tumor cell extravasation, cell migration and the role of the immunosystem is crucial in creating targeted and patient-specific cancer therapies. We created an in-vitro microfluidic cell...
4.
Adriani G, Ma D, Pavesi A, Goh E, Kamm R
Annu Int Conf IEEE Eng Med Biol Soc
. 2016 Jan;
2015:338-41.
PMID: 26736268
The need for a blood-brain barrier (BBB) model that accurately mimics the physiological characteristics of the in-vivo situation is well-recognized by researchers in academia and industry. However, there is currently...
5.
Bersini S, Jeon J, Moretti M, Kamm R
Drug Discov Today
. 2013 Dec;
19(6):735-42.
PMID: 24361339
A crucial event in the metastatic cascade is the extravasation of circulating cancer cells from blood capillaries to the surrounding tissues. The past 5 years have been characterized by a...
6.
Borau C, Kamm R, Garcia-Aznar J
Phys Biol
. 2011 Nov;
8(6):066008.
PMID: 22120116
Cell migration is essential for tissue development in different physiological and pathological conditions. It is a complex process orchestrated by chemistry, biological factors, microstructure and surrounding mechanical properties. Focusing on...
7.
Lee S, Chunsrivirot S, Kamm R, Mofrad M
Biophys J
. 2008 Apr;
95(4):2027-36.
PMID: 18408041
Cells can sense mechanical force in regulating focal adhesion assembly. One vivid example is the force-induced recruitment of vinculin to reinforce initial contacts between a cell and the extracellular matrix....
8.
Sieminski A, Semino C, Gong H, Kamm R
J Biomed Mater Res A
. 2008 Jan;
87(2):494-504.
PMID: 18186067
Appropriate choice of biomaterial supports is critical for the study of capillary morphogenesis in vitro as well as to support vascularization of engineered tissues in vivo. Self-assembling peptides are a...
9.
Sieminski A, Was A, Kim G, Gong H, Kamm R
Cell Biochem Biophys
. 2007 Oct;
49(2):73-83.
PMID: 17906362
Improving our ability to control capillary morphogenesis has implications for not only better understanding of basic biology, but also for applications in tissue engineering and in vitro testing. Numerous biomaterials...
10.
Force-induced unfolding of the focal adhesion targeting domain and the influence of paxillin binding
Mofrad M, Golji J, Abdul Rahim N, Kamm R
Mech Chem Biosyst
. 2006 Jun;
1(4):253-65.
PMID: 16783922
Membrane-bound integrin receptors are linked to intracellular signaling pathways through focal adhesion kinase (FAK). FAK tends to colocalize with integrin receptors at focal adhesions through its C-terminal focal adhesion targeting...