R Chess-Williams
Overview
Explore the profile of R Chess-Williams including associated specialties, affiliations and a list of published articles.
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55
Citations
1025
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Recent Articles
1.
Davis B, Wiener M, Chapple C, Sellers D, Chess-Williams R
Auton Autacoid Pharmacol
. 2015 Mar;
34(3-4):41-9.
PMID: 25790239
Alpha1 -adrenoceptor antagonists can cause ejaculatory dysfunction as an adverse effect. Contractions of the human vas deferens are mediated via α1A -adrenoceptors, and this study investigated whether the low affinity...
2.
Cheng Y, Mansfield K, Allen W, Chess-Williams R, Burcher E, Moore K
Biomed Res Int
. 2014 Jun;
2014:204604.
PMID: 24971316
ATP is an important mediator of urgency in women with detrusor overactivity (DO). In order to understand how different degrees of bladder stretch elicited ATP release in DO patients compared...
3.
McDermott C, Chess-Williams R, Mills K, Kang S, Farr S, Grant G, et al.
Toxicol In Vitro
. 2013 May;
27(6):1693-8.
PMID: 23665401
The effects of pseudomonal virulence factor pyocyanin, and LPS from Pseudomonas aeruginosa and Escherichia coli on urothelial mediator release and cytokine production were examined. RT4 urothelial cells were treated with...
4.
Moro C, Chess-Williams R
Auton Autacoid Pharmacol
. 2012 Sep;
32(3 Pt 4):53-9.
PMID: 22994938
Acetylcholine, and to a lesser extent ATP, mediates neurogenic contractions of bladder smooth muscle. Recently, the urothelium and lamina propria have also been shown to have contractile properties, but the...
5.
Mills K, Chess-Williams R
Auton Autacoid Pharmacol
. 2009 Jul;
29(3):85-95.
PMID: 19566748
1 The internal anal sphincter (IAS) has a spontaneous tone and is the main contributor to the maintenance of faecal continence. The spontaneous resting tone exhibited by the sphincter can...
6.
Mills K, Hausman N, Chess-Williams R
Br J Pharmacol
. 2008 Jun;
155(1):110-7.
PMID: 18516067
Background And Purpose: The internal anal sphincter has been shown to contract in response to alpha1-adrenoceptor stimulation and therefore alpha1-adrenoceptor agonists may be useful in treating faecal incontinence. This study...
7.
Sadananda P, Chess-Williams R, Burcher E
Br J Pharmacol
. 2008 Feb;
153(7):1465-73.
PMID: 18264120
Background And Purpose: The bladder urothelium is now known to have active properties. Our aim was to investigate the contractile properties of the urinary mucosa in response to the tachykinin...
8.
Daly D, Rong W, Chess-Williams R, Chapple C, Grundy D
J Physiol
. 2007 Jul;
583(Pt 2):663-74.
PMID: 17627983
Understanding bladder afferent pathways may reveal novel targets for therapy of lower urinary tract disorders such as overactive bladder syndrome and cystitis. Several potential candidate molecules have been postulated as...
9.
Chetty N, Coupar I, Chess-Williams R, Kerr K
Naunyn Schmiedebergs Arch Pharmacol
. 2007 Jul;
375(6):359-68.
PMID: 17607564
The aim of this study was to demonstrate the presence of 5-HT(3) receptors in the mouse bladder and to determine their location. Bladder strips from female mice were set up...
10.
Bagot K, Chess-Williams R
Auton Autacoid Pharmacol
. 2006 Sep;
26(4):345-53.
PMID: 16968473
Sympathetically mediated urethral tone is essential for the maintenance of continence and involves the activation of postjunctional alpha(1)-adrenoceptors. This study characterizes the alpha(1)-adrenoceptor subtypes responsible for mediating contraction of the...