R C Sears
Overview
Explore the profile of R C Sears including associated specialties, affiliations and a list of published articles.
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10
Citations
280
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Recent Articles
1.
Ostermann A, Wunderlich C, Schneiders L, Vogt M, Woeste M, Belgardt B, et al.
Nat Metab
. 2020 Jul;
1(3):371-389.
PMID: 32694718
Obesity promotes the development of insulin resistance and increases the incidence of colitis-associated cancer (CAC), but whether a blunted insulin action specifically in intestinal epithelial cells (IECs) affects CAC is...
2.
Langer E, Kendsersky N, Daniel C, Kuziel G, Pelz C, Murphy K, et al.
Oncogene
. 2017 Oct;
37(8):1005-1019.
PMID: 29084210
During normal tumor growth and in response to some therapies, tumor cells experience acute or chronic deprivation of nutrients and oxygen and induce tumor vascularization. While this occurs predominately through...
3.
Mannava S, Omilian A, Wawrzyniak J, Fink E, Zhuang D, Miecznikowski J, et al.
Oncogene
. 2011 Aug;
31(12):1484-92.
PMID: 21822300
Oncoprotein C-MYC is overexpressed in human metastatic melanomas and melanoma-derived cells where it is required for the suppression of oncogene-induced senescence (OIS). The genetic events that maintain high levels of...
4.
Ma J, Arnold H, Lilly M, Sears R, Kraft A
Oncogene
. 2007 Feb;
26(35):5145-53.
PMID: 17297438
The Pim protein kinases are serine threonine protein kinases that regulate important cellular signaling pathway molecules, and enhance the ability of c-Myc to induce lymphomas. We demonstrate that a cascade...
5.
Malempati S, Tibbitts D, Cunningham M, Akkari Y, Olson S, Fan G, et al.
Leukemia
. 2006 Jul;
20(9):1572-81.
PMID: 16855632
Overexpression of the c-Myc oncoprotein is observed in a large number of hematopoietic malignancies, and transgenic animal models have revealed a potent role for c-Myc in the generation of leukemias...
6.
Hann S, Dixit M, Sears R, Sealy L
Genes Dev
. 1994 Oct;
8(20):2441-52.
PMID: 7958908
The myc proto-oncogene family has been implicated in multiple cellular processes, including proliferation, differentiation, and apoptosis. The Myc proteins, as heterodimers with Max protein, have been shown to function as...
7.
Sears R, Sealy L
Mol Cell Biol
. 1994 Jul;
14(7):4855-71.
PMID: 8007984
In this report we demonstrate that C/EBP beta is a major component of three EFII DNA binding complexes, EFIIa, EFIIb, and EFIIc, which we have previously shown to specifically recognize...
8.
Sears R, Sealy L
J Virol
. 1992 Nov;
66(11):6338-52.
PMID: 1328670
The EFII cis element is a 38-bp sequence at the 5' end of the Rous sarcoma virus long terminal repeat, extending from nucleotides -229 to -192 (with respect to the...
9.
Sears R, Kaplan M
Vision Res
. 1989 Jan;
29(11):1485-92.
PMID: 2635474
Partial bleaches of rhodopsin were made in either the proximal or distal halves of isolated Rana pipiens rod outer segments. The fluorescence of all-trans retinol was recorded 15, 60 and...
10.
Kaplan M, Iwata R, Sears R
Exp Eye Res
. 1987 May;
44(5):623-32.
PMID: 2887449
Monoclonal anti-tubulin antibodies were used to label microtubules in the connecting cilia and outer segments of retinal photoreceptors isolated from Rana pipiens. In paraformaldehyde-fixed rods from frogs maintained on diurnal...