R C Mifflin
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Explore the profile of R C Mifflin including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
991
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Recent Articles
1.
Mifflin R, Pinchuk I, Saada J, Powell D
Am J Physiol Gastrointest Liver Physiol
. 2011 Jan;
300(5):G684-96.
PMID: 21252048
The subepithelial intestinal myofibroblast is an important cell orchestrating many diverse functions in the intestine and is involved in growth and repair, tumorigenesis, inflammation, and fibrosis. The myofibroblast is but...
2.
Powell D, Pinchuk I, Saada J, Chen X, Mifflin R
Annu Rev Physiol
. 2010 Nov;
73:213-37.
PMID: 21054163
The mesenchymal elements of the intestinal lamina propria reviewed here are the myofibroblasts, fibroblasts, mural cells (pericytes) of the vasculature, bone marrow-derived stromal stem cells, smooth muscle of the muscularis...
3.
Pinchuk I, Mifflin R, Saada J, Powell D
Curr Gastroenterol Rep
. 2010 Aug;
12(5):310-8.
PMID: 20690004
The non-white blood cell mesenchymal elements of the intestinal lamina propria are the myofibroblasts, fibroblasts, pericytes, stromal stem cells, muscularis mucosae, and the smooth muscle of the villus core associated...
4.
Di Mari J, Saada J, Mifflin R, Valentich J, Powell D
Am J Physiol Gastrointest Liver Physiol
. 2007 Jul;
293(4):G719-28.
PMID: 17640979
Proinflammatory cytokines and eicosanoids are central players in intestinal inflammation. IL-1, a key cytokine associated with intestinal mucosal inflammation, induces COX-2 expression in human colonic myofibroblasts (CMF) and increased prostaglandin...
5.
Powell D, Adegboyega P, Di Mari J, Mifflin R
Am J Physiol Gastrointest Liver Physiol
. 2005 Jun;
289(1):G2-7.
PMID: 15961883
Intestinal myofibroblasts are alpha-smooth muscle actin-positive stromal cells that exist as a syncytium with fibroblasts and mural cells in the lamina propria of the gut. Through expression and secretion of...
6.
Saada J, Barrera C, Reyes V, Adegboyega P, Suarez G, Tamerisa R, et al.
Ann N Y Acad Sci
. 2005 Feb;
1029:379-81.
PMID: 15681786
Stromal cells, such as myofibroblasts and fibroblasts, represent a significant fraction of MHC class II-positive cells in the normal human colonic lamina propria, suggesting they may play an important role...
7.
Barrera C, Pinchuk I, Saada J, Suarez G, Bland D, Beswick E, et al.
Ann N Y Acad Sci
. 2005 Feb;
1029:313-8.
PMID: 15681769
Food poisoning due to staphylococcal enterotoxins (SEs) affects hundreds of thousands of people each year. Little is known about how SEs initiate immune responses and cause pathogenesis. Here, we demonstrate...
8.
Powell D, Mifflin R, Valentich J, Crowe S, Saada J, West A
Am J Physiol
. 1999 Aug;
277(2):C183-201.
PMID: 10444394
Intestinal subepithelial myofibroblasts (ISEMF) and the interstitial cells of Cajal are the two types of myofibroblasts identified in the intestine. Intestinal myofibroblasts are activated and proliferate in response to various...
9.
Powell D, Mifflin R, Valentich J, Crowe S, Saada J, West A
Am J Physiol
. 1999 Jul;
277(1):C1-9.
PMID: 10409103
Myofibroblasts are a unique group of smooth-muscle-like fibroblasts that have a similar appearance and function regardless of their tissue of residence. Through the secretion of inflammatory and anti-inflammatory cytokines, chemokines,...
10.
Kurosky A, Gorham E, van Heumen W, Garcia A, Smith J, Mifflin R
Invert Neurosci
. 1997 Mar;
2(4):261-71.
PMID: 9460236
We have screened an Aplysia atrial gland cDNA library using an egg-laying hormone (ELH) precursor probe and have isolated and characterized five different clones, four of which are full-length and...