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R A Shimkets

Explore the profile of R A Shimkets including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 1744
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11.
Chang S, Grunder S, Hanukoglu A, Rosler A, Mathew P, Hanukoglu I, et al.
Nat Genet . 1996 Mar; 12(3):248-53. PMID: 8589714
Autosomal recessive pseudohypoaldosteronism type I is a rare life-threatening disease characterized by severe neonatal salt wasting, hyperkalaemia, metabolic acidosis, and unresponsiveness to mineralocorticoid hormones. Investigation of affected offspring of consanguineous...
12.
Schild L, Canessa C, Shimkets R, Gautschi I, Lifton R, Rossier B
Proc Natl Acad Sci U S A . 1995 Jun; 92(12):5699-703. PMID: 7777572
We have studied the functional consequences of a mutation in the epithelial Na+ channel that causes a heritable form of salt-sensitive hypertension, Liddle disease. This mutation, identified in the original...
13.
Shimkets R, Warnock D, Bositis C, Hansson J, Schambelan M, GILL Jr J, et al.
Cell . 1994 Nov; 79(3):407-14. PMID: 7954808
Liddle's syndrome (pseudoaldosteronism) is an autosomal dominant form of human hypertension characterized by a constellation of findings suggesting constitutive activation of the amiloride-sensitive distal renal epithelial sodium channel. We demonstrate...