R A Seder
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Explore the profile of R A Seder including associated specialties, affiliations and a list of published articles.
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60
Citations
3792
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Recent Articles
1.
Oneko M, Cherop Y, Sang T, Gutman J, Wiegand R, Nyangau E, et al.
Vaccine
. 2020 May;
38(29):4592-4600.
PMID: 32444192
PfSPZ Vaccine, composed of radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites, is administered by direct venous inoculation (DVI) for maximal efficacy against malaria. A critical issue for advancing vaccines that...
2.
Epstein J, Tewari K, Lyke K, Sim B, Billingsley P, Laurens M, et al.
Science
. 2011 Sep;
334(6055):475-80.
PMID: 21903775
Our goal is to develop a vaccine that sustainably prevents Plasmodium falciparum (Pf) malaria in ≥80% of recipients. Pf sporozoites (PfSPZ) administered by mosquito bites are the only immunogens shown...
3.
Mendez S, Gurunathan S, Kamhawi S, Belkaid Y, Moga M, Skeiky Y, et al.
J Immunol
. 2001 Apr;
166(8):5122-8.
PMID: 11290794
DNA- and protein- based vaccines against cutaneous leishmaniasis due to Leishmania major were evaluated using a challenge model that more closely reproduces the pathology and immunity associated with sand fly-transmitted...
4.
Zhou P, Freidag B, Caldwell C, Seder R
J Immunol
. 2001 Feb;
166(3):1968-74.
PMID: 11160245
Protective immunity against primary and secondary infection by the fungus Histoplasma capsulatum (HC) is multifactorial, requiring cells of the innate and adaptive immune response. Effector mechanisms that could mediate intracellular...
5.
Seder R, Hill A
Nature
. 2000 Aug;
406(6797):793-8.
PMID: 10963610
Vaccines against a variety of infectious diseases represent one of the great triumphs of medicine. The immune correlates of protection induced by most current vaccines seem to be mediated by...
6.
Dybul M, Mercier G, Belson M, Hallahan C, Liu S, Perry C, et al.
J Immunol
. 2000 Jul;
165(3):1685-91.
PMID: 10903780
It has been suggested that CD4+ T cell proliferative responses to HIV p24 Ag may be important in the control of HIV infection. However, these responses are minimal or absent...
7.
Gurunathan S, Wu C, Freidag B, Seder R
Curr Opin Immunol
. 2000 Jul;
12(4):442-7.
PMID: 10899026
Over the past few years, major advances in several areas of immunology have provided a foundation for the rational design of vaccines against diseases requiring cellular immunity. Among these advances...
8.
Stobie L, Gurunathan S, Prussin C, Sacks D, Glaichenhaus N, Wu C, et al.
Proc Natl Acad Sci U S A
. 2000 Jul;
97(15):8427-32.
PMID: 10890924
IL-12 plays a central role in both the induction and magnitude of a primary Th1 response. A critical question in designing vaccines for diseases requiring Th1 immunity such as Mycobacterium...
9.
Gurunathan S, Stobie L, Prussin C, Sacks D, Glaichenhaus N, Iwasaki A, et al.
J Immunol
. 2000 Jul;
165(2):915-24.
PMID: 10878366
Protective immunity against Leishmania major generated by DNA encoding the LACK (Leishmania homologue of receptor for activated C kinase) Ag has been shown to be more durable than vaccination with...
10.
Gurunathan S, Klinman D, Seder R
Annu Rev Immunol
. 2000 Jun;
18:927-74.
PMID: 10837079
The development and widespread use of vaccines against infectious agents have been a great triumph of medical science. One reason for the success of currently available vaccines is that they...