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R A Rutherford

Explore the profile of R A Rutherford including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Banning A, Groves P, Buttery L, Wharton J, Rutherford R, Black P, et al.
Atherosclerosis . 1999 Jul; 145(1):17-32. PMID: 10428292
Objective: Nitric oxide produced by nitric oxide synthase appears to have an important role in the regulation of arterial tone, platelet adhesion and smooth muscle cell proliferation. Our aim was...
2.
Brown L, Rutherford R, Nunez D, Wharton J, Lowe D, Wilkins M
Cardiovasc Res . 1998 Apr; 36(3):363-71. PMID: 9534857
Objectives: This study examined the expression of the C-type receptor for the natriuretic peptide family (NPR-C) in the ventricles of normal and aortovenocaval (AV)-fistula rats, the latter a model of...
3.
Wharton J, Morgan K, Rutherford R, Catravas J, Chester A, Whitehead B, et al.
J Pharmacol Exp Ther . 1998 Jan; 284(1):323-36. PMID: 9435195
Cardiac expression of angiotensin II (Ang II) AT1 and AT2 receptor subtypes is species dependent, and changes in their relative proportion may influence myocardial hypertrophy and fibrosis. Regional differences in...
4.
Rutherford R, Smith A, Waibel R, Schubiger P
Int J Cancer . 1997 Jul; 72(3):522-9. PMID: 9247299
The basic amino acid L-lysine was administered to mice in an attempt to circumvent unwanted renal accumulation of 67Cu-labelled F(ab')2 fragments derived from the anti-NCAM IgG1, SEN7 and anti-CEA IgG1...
5.
Lefroy D, Wharton J, Crake T, Knock G, Rutherford R, Suzuki T, et al.
J Mol Cell Cardiol . 1996 Feb; 28(2):429-40. PMID: 8729073
The plasma and cardiac renin-angiotensin systems may be activated after myocardial infarction. The myocardium may therefore be exposed to increased concentrations of angiotension II, which may contribute to myocardial injury....
6.
Rutherford R, McCarthy A, Sullivan M, Elder M, Polak J, Wharton J
Br J Pharmacol . 1995 Dec; 116(8):3099-109. PMID: 8719783
1. It has been suggested that a deficiency of nitric oxide (NO) may explain many of the pathophysiological features of pre-eclampsia (PE) and intra-uterine (foetal) growth retardation (IUGR). To elucidate...
7.
Rutherford R, Matsuda Y, Wilkins M, Polak J, Wharton J
Br J Pharmacol . 1994 Nov; 113(3):931-9. PMID: 7858888
1. The renal actions of natriuretic peptides are dictated by the distribution of guanylyl cyclase-linked (NPRA and NPRB) and non-guanylyl cyclase-linked (NPRC) receptors. Natriuretic peptide receptors have previously been distinguished...
8.
Rutherford R, Wharton J, McCarthy A, Gordon L, Sullivan M, Elder M, et al.
Br J Pharmacol . 1993 Jun; 109(2):544-52. PMID: 8358555
1. The localization and differential distribution of endothelin (ET) receptor subtypes (ETA and ETB) was investigated in sections of human placenta by use of quantitative in vitro autoradiography and receptor...
9.
Wharton J, Rutherford R, Walsh D, Mapp P, Knock G, Blake D, et al.
Arthritis Rheum . 1992 Aug; 35(8):894-9. PMID: 1642655
Objective: To determine the localization of endothelin binding sites and immunoreactivity in human synovial tissues. Methods: Quantitative in vitro autoradiographic and immunohistochemical techniques were used to localize and characterize 125I-labeled...
10.
Walsh D, Mapp P, Wharton J, Rutherford R, Kidd B, Revell P, et al.
Ann Rheum Dis . 1992 Mar; 51(3):313-7. PMID: 1374227
The neuropeptide substance P is found in perivascular and free unmyelinated nerve fibres in human synovial tissue. Quantitative receptor autoradiography was used to show specific, high affinity (Kd = 0.75...