R A Holmgren
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Explore the profile of R A Holmgren including associated specialties, affiliations and a list of published articles.
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7
Citations
221
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Recent Articles
1.
Lefers M, Wang Q, Holmgren R
Dev Biol
. 2001 Jul;
236(2):411-20.
PMID: 11476581
Much of our understanding of the Hedgehog (Hh) signaling pathway comes from Drosophila, where a gradient of Hh signaling regulates the function of the transcription factor Cubitus interruptus (Ci) at...
2.
Wang Q, Holmgren R
Development
. 2000 Jun;
127(14):3131-9.
PMID: 10862750
The Hedgehog (Hh) signal is transduced via Cubitus interruptus (Ci) to specify cell fates in the Drosophila wing. In the absence of Hh, the 155 kDa full-length form of Ci...
3.
Wang Q, Holmgren R
Development
. 1999 Oct;
126(22):5097-106.
PMID: 10529426
Cubitus interruptus (Ci), a Drosophila transcription factor, mediates Hedgehog (Hh) signaling during the patterning of embryonic epidermis and larval imaginal discs. In the absence of Hh signal, Ci is cleaved...
4.
Macdonald R, Musacchio A, Holmgren R, Saraste M
Proc Natl Acad Sci U S A
. 1994 Feb;
91(4):1299-303.
PMID: 8108405
The tryptophan that is highly conserved among repeating structural units of spectrin is reported to promote the conformational stability of one such unit of chicken brain alpha-spectrin. Four constructs were...
5.
Winick J, Abel T, Leonard M, MICHELSON A, Holmgren R, Maniatis T, et al.
Development
. 1993 Dec;
119(4):1055-65.
PMID: 7916677
The GATA transcription factors are a family of C4 zinc finger-motif DNA-binding proteins that play defined roles in hematopoiesis as well as presumptive roles in other tissues where they are...
6.
Holmgren R, Engel J
Genes Dev
. 1992 Feb;
6(2):161-5.
PMID: 1346608
In summary (and probably to no one's genuine surprise), it seems clear that some of the key themes in the mechanisms employed during development reiterate themselves throughout the animal kingdom....
7.
Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila
Orenic T, Slusarski D, Kroll K, Holmgren R
Genes Dev
. 1990 Jun;
4(6):1053-67.
PMID: 2166702
The segment polarity mutation, cubitus interruptus Dominant (ciD), of Drosophila melanogaster causes defects in the posterior half of every embryonic segment. We cloned sequences from the ciD region on the...