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R A Fratti

Explore the profile of R A Fratti including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 462
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Recent Articles
1.
Fratti R, Backer J, Gruenberg J, Corvera S, Deretic V
J Cell Biol . 2001 Aug; 154(3):631-44. PMID: 11489920
Phagosomal biogenesis is a fundamental biological process of particular significance for the function of phagocytic and antigen-presenting cells. The precise mechanisms governing maturation of phagosomes into phagolysosomes are not completely...
2.
Fratti R, Vergne I, Chua J, Skidmore J, Deretic V
Electrophoresis . 2000 Nov; 21(16):3378-85. PMID: 11079558
The biogenesis and maturation of phagosomes is an area of study which has been employing aspects of proteomic analyses and variations on that theme by identifying components on isolated organelles...
3.
Deretic V, Fratti R
Mol Microbiol . 1999 Apr; 31(6):1603-9. PMID: 10209735
The arrest of Mycobacterium tuberculosis phagosome maturation in infected macrophages is a phenomenon of dual significance both for the pathogenesis of tuberculosis and as a model system to study interference...
4.
Via L, Fratti R, McFalone M, Deretic D, Deretic V
J Cell Sci . 1998 May; 111 ( Pt 7):897-905. PMID: 9490634
One of the major mechanisms permitting intracellular pathogens to parasitize macrophages is their ability to alter maturation of the phagosome or affect its physical integrity. These processes are opposed by...
5.
Fratti R, Belanger P, Sanati H, Ghannoum M
J Chemother . 1998 Apr; 10(1):7-16. PMID: 9531069
In this study, we investigated how voriconazole affects specific endothelial cell interactions utilizing both fluconazole-susceptibles and resistantR Candida albicans strains (C. albicansS and C. albicansR, respectively) as well as Candida...
6.
Deretic V, Via L, Fratti R, Deretic D
Electrophoresis . 1998 Apr; 18(14):2542-7. PMID: 9527483
One of the most prominent features of pathogenic mycobacteria, which include the potent human pathogens Mycobacterium tuberculosis and Mycobacterium leprae and their opportunistic relatives Mycobacterium avium and Mycobacterium marinum, is...
7.
Fratti R, Belanger P, Ghannoum M, Edwards Jr J, Filler S
Infect Immun . 1998 Jan; 66(1):191-6. PMID: 9423857
Although it is known that Candida albicans causes endothelial cell injury, in vitro and in vivo, the mechanism by which this process occurs remains unknown. Iron is critical for the...
8.
Fratti R, Ghannoum M, Edwards Jr J, Filler S
Infect Immun . 1996 Nov; 64(11):4714-8. PMID: 8890230
Once Candida albicans comes in contact with endothelial cells, it induces cellular injury. This endothelial cell injury may be a mechanism by which blood-borne organisms escape from the intravascular compartment...