J E Edwards Jr
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Explore the profile of J E Edwards Jr including associated specialties, affiliations and a list of published articles.
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75
Citations
2122
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Recent Articles
1.
Spellberg B, Miller L, Kuo M, Bradley J, Scheld W, Edwards Jr J
Infection
. 2007 Jun;
35(3):167-74.
PMID: 17565458
Background: Over the last two decades, an alarming rise in infections caused by antibiotic-resistant microbes has been paralleled by an equally alarming decline in the development of new antibiotics to...
2.
3.
Rex J, Walsh T, Nettleman M, Anaissie E, Bennett J, Bow E, et al.
Clin Infect Dis
. 2001 Jun;
33(1):95-106.
PMID: 11389501
Studies of invasive fungal infections have been and remain difficult to implement. Randomized clinical trials of fungal infections are especially slow and expensive to perform because it is difficult to...
4.
Miller L, Hajjeh R, Edwards Jr J
Clin Infect Dis
. 2001 Mar;
32(7):1110.
PMID: 11264044
No abstract available.
5.
Clemons K, Calich V, Burger E, Filler S, Grazziutti M, Murphy J, et al.
Med Mycol
. 2001 Feb;
38 Suppl 1:99-111.
PMID: 11204170
The interactions of host cells and fungi during infection represent a complex interplay. Although T helper 1 (Th1)-mediated immunity is primarily responsible for acquired resistance to Paracoccidioides brasiliensis, studies have...
6.
Spellberg B, Edwards Jr J
Clin Infect Dis
. 2000 Dec;
32(1):76-102.
PMID: 11118387
T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-gamma, and lymphotoxin-alpha and stimulate type 1 immunity, which is characterized by intense phagocytic activity. Conversely, Th2 cells secrete IL-4,...
7.
Davis D, Edwards Jr J, Mitchell A, Ibrahim A
Infect Immun
. 2000 Sep;
68(10):5953-9.
PMID: 10992507
The ability of Candida albicans to respond to diverse environments is critical for its success as a pathogen. The RIM101 pathway controls gene expression and the yeast-to-hyphal transition in C....
8.
Tsuchimori N, Sharkey L, Fonzi W, French S, Edwards Jr J, Filler S
Infect Immun
. 2000 Mar;
68(4):1997-2002.
PMID: 10722594
The Candida albicans gene HWP1 encodes a surface protein that is required for normal hyphal development in vitro. We used mutants lacking one or both alleles of HWP1 to investigate...
9.
Wiblin T, Blumberg H, Saiman L, Patterson J, Rinaldi M, Pfaller M, et al.
Clin Infect Dis
. 1999 Sep;
29(2):253-8.
PMID: 10476721
Candida species are the fourth most frequent cause of nosocomial bloodstream infections, and 25%-50% occur in critical care units. During an 18-month prospective study period, all patients admitted for >...
10.
Rieg G, Fu Y, Ibrahim A, Zhou X, Filler S, Edwards Jr J
Infect Immun
. 1999 Jun;
67(7):3193-8.
PMID: 10377090
The disruption of a specific gene in Candida albicans is commonly used to determine the function of the gene product. We disrupted AAF1, a gene of C. albicans that causes...