R A Dobson
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Explore the profile of R A Dobson including associated specialties, affiliations and a list of published articles.
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6
Citations
46
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Recent Articles
1.
Sedlock D, Dobson R, Deuel D, LESHER G, Rake J
Antimicrob Agents Chemother
. 1990 Apr;
34(4):568-75.
PMID: 2344163
The antibacterial activity of a new 7-dimethylpyridinyl quinolone, WIN 57273, was assessed by using in vitro and in vivo models. Agar inclusion and broth dilution in vitro tests revealed broad-spectrum...
2.
Cornett J, WAGNER R, Dobson R, Wentland M, Bailey D
Antimicrob Agents Chemother
. 1985 Jan;
27(1):4-10.
PMID: 3885845
WIN 49375 (amifloxacin) is a synthetic antibacterial agent of the quinolone class. It is similar in chemical structure to pefloxacin but differs by containing a methylamino, rather than an ethyl,...
3.
Wentland M, Bailey D, Cornett J, Dobson R, Powles R, WAGNER R
J Med Chem
. 1984 Sep;
27(9):1103-8.
PMID: 6381730
A series of novel 3-quinolinecarboxylic acid derivatives have been prepared and their antibacterial activity evaluated. These derivatives are characterized by fluorine attached to the 6-position and substituted amino groups appended...
4.
Johnson R, Soria A, OCONNOR J, Dobson R
J Med Chem
. 1981 Nov;
24(11):1314-9.
PMID: 7310807
The syntheses of 1-(arylamino)-1H-pyrroles and 4-(1H-pyrrol-1-ylimino)-2-5-cyclohexadienes are described. Several of these compounds express in vitro antibacterial activity or can be metabolized to show in vitro antibacterial activity, and a few...
5.
Dobson R, OCONNOR J, Poulin S, KUNDSIN R, Smith T, Came P
Antimicrob Agents Chemother
. 1980 Nov;
18(5):738-40.
PMID: 6778385
The antimicrobial activity of rosoxacin, a new quinoline antibacterial compound, was determined against the causative organisms of three sexually transmitted diseases. Rosoxacin demonstrated a high degree of activity against Neisseria...
6.
Came P, OCONNOR J, Dobson R, WAGNER R, Fabian R
Antimicrob Agents Chemother
. 1979 Dec;
16(6):813-22.
PMID: 533261
Win 42122-2 is a new aminoglycoside antibiotic obtained from a mutant strain of Micromonospora purpurea. In vitro and in vivo comparisons of Win 42122-2 with gentamicin and amikacin revealed that...