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Quanhong Lei

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Articles 11
Citations 507
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Recent Articles
1.
Wang R, DeGruttola V, Lei Q, Mayer K, Redline S, Hazra A, et al.
Contemp Clin Trials . 2020 Oct; 100:106176. PMID: 33045402
Objectives: To determine the effect of vitamin D supplementation on disease progression and post-exposure prophylaxis for COVID-19 infection. We hypothesize that high-dose vitamin D3 supplementation will reduce risk of hospitalization/death...
2.
Wirth K, Gaolathe T, Pretorius Holme M, Mmalane M, Kadima E, Chakalisa U, et al.
Lancet HIV . 2020 Jun; 7(6):e422-e433. PMID: 32504575
Background: In settings with high HIV prevalence and treatment coverage, such as Botswana, it is unknown whether uptake of HIV prevention and treatment interventions can be increased further. We sought...
3.
Makhema J, Wirth K, Pretorius Holme M, Gaolathe T, Mmalane M, Kadima E, et al.
N Engl J Med . 2019 Jul; 381(3):230-242. PMID: 31314967
Background: The feasibility of reducing the population-level incidence of human immunodeficiency virus (HIV) infection by increasing community coverage of antiretroviral therapy (ART) and male circumcision is unknown. Methods: We conducted...
4.
Gaolathe T, Wirth K, Pretorius Holme M, Makhema J, Moyo S, Chakalisa U, et al.
Lancet HIV . 2016 Apr; 3(5):e221-30. PMID: 27126489
Background: HIV programmes face challenges achieving high rates of HIV testing and treatment needed to optimise health and to reduce transmission. We used data from the Botswana Combination Prevention Project...
5.
Sudfeld C, Lei Q, Chinyanga Y, Tumbare E, Khan N, Dapaah-Siakwan F, et al.
J Acquir Immune Defic Syndr . 2016 Apr; 73(2):182-9. PMID: 27116046
Background: HIV-exposed uninfected (HEU) children experience increased mortality compared with their HIV-unexposed uninfected (HUU) peers. It is unclear whether HEU children are also at increased risk for undernutrition, a modifiable...
6.
Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, Van Widenfelt E, et al.
J Int AIDS Soc . 2015 Jun; 18:19918. PMID: 26028155
Introduction: It would be useful to understand which populations are not reached by home-based HIV-1 testing and counselling (HTC) to improve strategies aimed at linking these individuals to care and...
7.
Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M
AIDS Res Hum Retroviruses . 2015 Jan; 31(5):531-42. PMID: 25560745
To improve the methodology of HIV cluster analysis, we addressed how analysis of HIV clustering is associated with parameters that can affect the outcome of viral clustering. The extent of...
8.
Novitsky V, Moyo S, Lei Q, DeGruttola V, Essex M
AIDS Res Hum Retroviruses . 2014 Oct; 30(12):1226-35. PMID: 25275430
Identifying and monitoring HIV clusters could be useful in tracking the leading edge of HIV transmission in epidemics. Currently, greater specificity in the definition of HIV clusters is needed to...
9.
Wang R, Goyal R, Lei Q, Essex M, de Gruttola V
Clin Trials . 2014 Mar; 11(3):309-318. PMID: 24651566
Background Cluster randomized trials have been utilized to evaluate the effectiveness of HIV prevention strategies on reducing incidence. Design of such studies must take into account possible correlation of outcomes...
10.
Novitsky V, Bussmann H, Logan A, Moyo S, Van Widenfelt E, Okui L, et al.
PLoS One . 2013 Dec; 8(12):e80589. PMID: 24349005
Background: Determining patterns of HIV transmission is increasingly important for the most efficient use of modern prevention interventions. HIV phylogeny can provide a better understanding of the mechanisms underlying HIV...