Quang M Trinh
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Explore the profile of Quang M Trinh including associated specialties, affiliations and a list of published articles.
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20
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1126
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Recent Articles
11.
Borozan I, Zaidi S, Harrison T, Phipps A, Zheng J, Lee S, et al.
Cancer Epidemiol Biomarkers Prev
. 2021 Nov;
31(1):210-220.
PMID: 34737207
Background: () activates oncogenic signaling pathways and induces inflammation to promote colorectal carcinogenesis. Methods: We characterized and its subspecies in colorectal tumors and examined associations with tumor characteristics and colorectal...
12.
Skowron P, Farooq H, Cavalli F, Morrissy A, Ly M, Hendrikse L, et al.
Nat Commun
. 2021 Mar;
12(1):1749.
PMID: 33741928
Sonic hedgehog medulloblastoma encompasses a clinically and molecularly diverse group of cancers of the developing central nervous system. Here, we use unbiased sequencing of the transcriptome across a large cohort...
13.
Zaidi S, Harrison T, Phipps A, Steinfelder R, Trinh Q, Qu C, et al.
Nat Commun
. 2020 Jul;
11(1):3644.
PMID: 32686686
Colorectal cancer (CRC) is a biologically heterogeneous disease. To characterize its mutational profile, we conduct targeted sequencing of 205 genes for 2,105 CRC cases with survival data. Our data shows...
14.
Kalatskaya I, Trinh Q, Spears M, McPherson J, Bartlett J, Stein L
Genome Med
. 2017 Jun;
9(1):59.
PMID: 28659176
Background: A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the...
15.
Wang D, Pham N, Tong J, Sakashita S, Allo G, Kim L, et al.
Int J Cancer
. 2016 Oct;
140(3):662-673.
PMID: 27750381
Availability of lung cancer models that closely mimic human tumors remains a significant gap in cancer research, as tumor cell lines and mouse models may not recapitulate the spectrum of...
16.
Chen P, Yin J, Yu H, Yuan T, Fernandez M, Yung C, et al.
Proc Natl Acad Sci U S A
. 2014 Jul;
111(31):11473-8.
PMID: 25049390
Noonan syndrome (NS) is a relatively common genetic disorder, characterized by typical facies, short stature, developmental delay, and cardiac abnormalities. Known causative genes account for 70-80% of clinically diagnosed NS...
17.
Shlush L, Zandi S, Mitchell A, Chen W, Brandwein J, Gupta V, et al.
Nature
. 2014 Feb;
506(7488):328-33.
PMID: 24522528
In acute myeloid leukaemia (AML), the cell of origin, nature and biological consequences of initiating lesions, and order of subsequent mutations remain poorly understood, as AML is typically diagnosed without...
18.
Peltekova V, Lemire M, Qazi A, Zaidi S, Trinh Q, Bielecki R, et al.
Int J Cancer
. 2013 Oct;
134(10):2330-41.
PMID: 24154973
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide....
19.
Trinh Q, Jen F, Zhou Z, Chu K, Perry M, Kephart E, et al.
BMC Genomics
. 2013 Jul;
14:494.
PMID: 23875683
Background: Funded by the National Institutes of Health (NIH), the aim of the Model Organism ENCyclopedia of DNA Elements (modENCODE) project is to provide the biological research community with a...
20.
Grant R, Al-Sukhni W, Borgida A, Holter S, Kanji Z, McPherson T, et al.
Hum Genomics
. 2013 Apr;
7:11.
PMID: 23561644
We sequenced 11 germline exomes from five families with familial pancreatic cancer (FPC). One proband had a germline nonsense variant in ATM with somatic loss of the variant allele. Another...