Qizhou Lian
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Explore the profile of Qizhou Lian including associated specialties, affiliations and a list of published articles.
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98
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3879
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Recent Articles
1.
Jiang D, Yu J, Wu X, Yu X, Jin P, Zheng H, et al.
Invest Ophthalmol Vis Sci
. 2025 Mar;
66(3):14.
PMID: 40048188
Purpose: This study aimed to investigate the therapeutic potential of isolated mitochondrial transplantation for the restoration of corneal surface injury in mice after corneal chemical burn. Methods: Mitochondria were isolated...
2.
Zhou X, Ma C, Zhang X, Xu X, Duan F, Kou M, et al.
Mol Ther Nucleic Acids
. 2025 Mar;
36(1):102469.
PMID: 40027885
X-linked adrenoleukodystrophy (X-ALD) is a common peroxisomal disorder caused by mutations in the gene, leading to the accumulation of very long-chain fatty acids (VLCFAs). This progressive neurodegenerative disease manifests in...
3.
Wu Y, Meng M, Liu Y, Zeng R, Feng J, Lian Q, et al.
Dtsch Arztebl Int
. 2025 Feb;
(Forthcoming).
PMID: 39936588
Background: It is crucial to identify modifiable preventive measures to mitigate the risk of colorectal cancer (CRC) among patients with type 2 diabetes (T2D), a high-risk group for CRC. We...
4.
Chen J, Li Z, Zheng G, Cao L, Guo Y, Lian Q, et al.
NPJ Precis Oncol
. 2024 Nov;
8(1):258.
PMID: 39521913
This study investigates the role of RNF4-mediated ubiquitination and degradation of PDHA1 in colorectal cancer (CRC) metabolism and metastasis. Integrating (The Cancer Genome Atlas) TCGA and Clinical Proteomic Tumor Analysis...
5.
Su Q, Long Y, Gou D, Quan J, Lian Q
Brief Bioinform
. 2024 Oct;
25(6).
PMID: 39428128
We introduce a groundbreaking approach: the minimum free energy-based Gaussian Self-Benchmarking (MFE-GSB) framework, designed to combat the myriad of biases inherent in RNA-seq data. Central to our methodology is the...
6.
Wu K, Xu X, Wu M, Li X, Hoque M, Li G, et al.
Nat Commun
. 2024 Oct;
15(1):8624.
PMID: 39366973
M1 macrophages induce protective immunity against infection, but also contribute to metabolic and inflammatory diseases. Here we show that the E3 ubiquitin ligase, MDM2, promotes the glycolytic and inflammatory activities...
7.
Su Q, Long Y, Gou D, Quan J, Lian Q
BMC Genomics
. 2024 Sep;
25(1):904.
PMID: 39350040
Background: RNA sequencing is a vital technique for analyzing RNA behavior in cells, but it often suffers from various biases that distort the data. Traditional methods to address these biases...
8.
Jiang R, Huang W, Qiu X, Chen J, Luo R, Zeng R, et al.
Brief Bioinform
. 2024 Jul;
25(4).
PMID: 39038939
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which current treatments are limited and drug development costs are prohibitive. Identifying drug targets for ASD is crucial for the...
9.
Chen Q, Ao L, Zhao Q, Tang L, Xiong Y, Yuan Y, et al.
J Adv Res
. 2024 Jun;
PMID: 38944238
Introduction: The immunosuppressive capacity of mesenchymal stem cells (MSCs) is dependent on the "license" of several pro-inflammatory factors to express immunosuppressive molecular profiles, which determines the therapeutic efficacy of MSCs...
10.
Zhang Z, Jiang H, Huang L, Liu S, Zhou X, Cai Y, et al.
Protein Cell
. 2024 Jun;
16(1):16-27.
PMID: 38916435
Metachromatic leukodystrophy (MLD) is an inherited disease caused by a deficiency of the enzyme arylsulfatase A (ARSA). Lentivirus-modified autologous hematopoietic stem cell gene therapy (HSCGT) has recently been approved for...