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Qiufang Deng

Explore the profile of Qiufang Deng including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 558
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Recent Articles
1.
Tian Y, Li P, Wu Z, Deng Q, Pan B, Stringer K, et al.
Front Immunol . 2021 Dec; 12:761345. PMID: 34950139
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection that often results in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). An emerging mechanism of sepsis-induced...
2.
Tian Y, Qu S, Alam H, Williams A, Wu Z, Deng Q, et al.
JCI Insight . 2020 Oct; 5(20). PMID: 33055424
Peptidylarginine deiminases (PADs) are a family of calcium-dependent enzymes that are involved in a variety of human disorders, including cancer and autoimmune diseases. Although targeting PAD4 has shown no benefit...
3.
Huang Y, Deng Q, Yang L, Ma J, Wang Z, Huang D, et al.
Pain Res Manag . 2020 Oct; 2020:2537075. PMID: 33014212
Background: Knee osteoarthritis (KOA) is a common degenerative disease associated with joint dysfunction and pain. Ultrasound-guided radiofrequency (RF) may be a promising therapy in the treatment of chronic pain for...
4.
Magupalli V, Negro R, Tian Y, Hauenstein A, Di Caprio G, Skillern W, et al.
Science . 2020 Sep; 369(6510). PMID: 32943500
Inflammasomes are supramolecular complexes that play key roles in immune surveillance. This is accomplished by the activation of inflammatory caspases, which leads to the proteolytic maturation of interleukin 1β (IL-1β)...
5.
Siddiqui A, Bhatti U, Deng Q, Biesterveld B, Tian Y, Wu Z, et al.
Surg Infect (Larchmt) . 2020 Aug; 22(4):421-426. PMID: 32833601
Sepsis causes millions of deaths on a global scale annually. Activation of peptidylarginine deiminase (PAD) enzymes in sepsis causes citrullination of histones, which results in neutrophil extracellular trap formation and...
6.
Wu Z, Deng Q, Pan B, Alam H, Tian Y, Bhatti U, et al.
Inflammation . 2020 Apr; 43(4):1436-1445. PMID: 32239392
Endotoxemia induced by lipopolysaccharide (LPS) is an extremely severe syndrome identified by global activation of inflammatory responses. Neutrophil extracellular traps (NETs) play an important role in the development of endotoxemia....
7.
Deng Q, Pan B, Alam H, Liang Y, Wu Z, Liu B, et al.
Front Immunol . 2020 Jan; 10:2957. PMID: 31998291
Sepsis results in millions of deaths every year, with acute lung injury (ALI) being one of the leading causes of mortality in septic patients. As neutrophil extracellular traps (NETs) are...
8.
Park Y, Ryu B, Deng Q, Pan B, Song Y, Tian Y, et al.
Small . 2019 Dec; 16(1):e1905611. PMID: 31793755
Bacterial infections leading to sepsis are a major cause of deaths in the intensive care unit. Unfortunately, no effective methods are available to capture the early onset of infectious sepsis...
9.
Su T, Xiao Y, Xiao Y, Guo Q, Li C, Huang Y, et al.
ACS Nano . 2019 Feb; 13(2):2450-2462. PMID: 30715852
Insulin resistance is the major pathological characteristic of type 2 diabetes, and the elderly often develop insulin resistance. However, the deep-seated mechanisms for aging-related insulin resistance remain unclear. Here, we...
10.
Williams A, Bhatti U, Dennahy I, Chtraklin K, Chang P, Graham N, et al.
J Vis Exp . 2018 Sep; (138). PMID: 30199035
Hemorrhage remains the leading cause of preventable deaths in trauma. Endovascular management of non-compressible torso hemorrhage has been at the forefront of trauma care in recent years. Since complete aortic...