Qiangfeng Cliff Zhang
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Explore the profile of Qiangfeng Cliff Zhang including associated specialties, affiliations and a list of published articles.
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77
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4664
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Recent Articles
1.
Liu M, Yue Y, Chen X, Xian K, Dong C, Shi M, et al.
Nature
. 2025 Feb;
PMID: 40011786
Substantial epigenetic resetting during early embryo development from fertilization to blastocyst formation ensures zygotic genome activation and leads to progressive cellular heterogeneities. Mapping single-cell epigenomic profiles of core histone modifications...
2.
Wang T, Huang W, Xu K, Sun Y, Zhang Q, Yan C, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
122(1):e2423943122.
PMID: 39739783
Despite the recent breakthrough in structure determination and prediction of proteins, the structural investigation of carbohydrates remains a challenge. Here, we report the cryo-EM analysis of a glycofibril found in...
3.
Mu K, Fei Y, Xu Y, Zhang Q
Nucleic Acids Res
. 2024 Nov;
53(D1):D211-D219.
PMID: 39546630
RNA molecules function in numerous biological processes by folding into intricate structures. Here we present RASP v2.0, an updated database for RNA structure probing data featuring a substantially expanded collection...
4.
Wang T, Li Z, Xu K, Huang W, Huang G, Zhang Q, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2417046121.
PMID: 39382995
Structural biology is experiencing a paradigm shift from targeted structural determination to structure-guided discovery of previously uncharacterized bioentities. We employed cryoelectron microscopy (cryo-EM) to analyze filtered water samples collected from...
5.
Piao M, Li P, Zeng X, Wang X, Kang L, Zhang J, et al.
Fundam Res
. 2024 Jun;
2(1):2-13.
PMID: 38933905
To enable diverse functions and precise regulation, an RNA sequence often folds into complex yet distinct structures in different cellular states. Probing RNA in its native environment is essential to...
6.
Deng J, Fang X, Huang L, Li S, Xu L, Ye K, et al.
Fundam Res
. 2024 Jun;
3(5):727-737.
PMID: 38933295
RNA molecules serve a wide range of functions that are closely linked to their structures. The basic structural units of RNA consist of single- and double-stranded regions. In order to...
7.
Li Y, Zhang J, Gao X, Zhang Q
Cell Syst
. 2024 Jun;
15(6):578-592.e7.
PMID: 38823396
Computational methods are desired for single-cell-resolution spatial transcriptomics (ST) data analysis to uncover spatial organization principles for how individual cells exert tissue-specific functions. Here, we present ST data analysis via...
8.
Yang R, Pan M, Guo J, Huang Y, Zhang Q, Deng T, et al.
Cell Rep
. 2024 Feb;
43(3):113833.
PMID: 38416642
Influenza A virus (IAV) represents a constant public health threat. The single-stranded, segmented RNA genome of IAV is replicated in host cell nuclei as a series of 8 ribonucleoprotein complexes...
9.
Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, et al.
Nat Struct Mol Biol
. 2024 Jan;
31(5):835-845.
PMID: 38196034
Selection of the pre-mRNA branch site (BS) by the U2 small nuclear ribonucleoprotein (snRNP) is crucial to prespliceosome (A complex) assembly. The RNA helicase PRP5 proofreads BS selection but the...
10.
Huang W, Xiong T, Zhao Y, Heng J, Han G, Wang P, et al.
Nat Genet
. 2024 Jan;
56(1):124-135.
PMID: 38195860
Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME), a computational pipeline that...