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Pu-Ste Liu

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Articles 22
Citations 1120
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Recent Articles
1.
Han J, Zheng D, Liu P, Wang S, Xie X
Cell Commun Signal . 2024 Oct; 22(1):475. PMID: 39367496
Peroxisomes are dynamic organelles involved in various cellular processes, including lipid metabolism, redox homeostasis, and intracellular metabolite transfer. Accumulating evidence suggests that peroxisomal homeostasis plays a crucial role in human...
2.
Zheng D, Jin S, Liu P, Ye J, Xie X
Arch Toxicol . 2024 Jul; 98(10):3191-3208. PMID: 38987487
Ferroptosis is a form of cell death that is induced by iron-mediated accumulation of lipid peroxidation. The involvement of ferroptosis in different pathophysiological conditions has offered new perspectives on potential...
3.
Zheng D, Li F, Wang S, Liu P, Xie X
Cell Mol Biol Lett . 2024 Feb; 29(1):26. PMID: 38368371
Background: The peroxisome is a dynamic organelle with variety in number, size, shape, and activity in different cell types and physiological states. Recent studies have implicated peroxisomal homeostasis in ferroptosis...
4.
Jin S, Liu P, Zheng D, Xie X
Apoptosis . 2023 Sep; 29(1-2):45-65. PMID: 37758940
Ferroptosis has been conceptualized as a novel cell death modality distinct from apoptosis, necroptosis, pyroptosis and autophagic cell death. The sensitivity of cellular ferroptosis is regulated at multiple layers, including...
5.
Zeng W, Li F, Jin S, Ho P, Liu P, Xie X
J Exp Clin Cancer Res . 2023 Sep; 42(1):245. PMID: 37740232
Macrophages are highly plastic in different tissues and can differentiate into functional subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of the most important innate immune cells implicated in...
6.
Liu P, Chen Y, Li X, Hsueh P, Tzeng S, Chen H, et al.
Nat Immunol . 2023 Aug; 24(9):1591. PMID: 37563312
No abstract available.
7.
Zeng W, Long X, Liu P, Xie X
Int J Cancer . 2023 Feb; 153(5):918-931. PMID: 36843262
Oncogene-induced hyper-proliferation in cancer cells is accompanied by the onset of different stresses, including DNA-replication stress, metabolic stress and oxidative stress. Excessive accumulation of reactive oxygen species (ROS) plays a...
8.
Liu P, Chen Y, Li X, Hsueh P, Tzeng S, Chen H, et al.
Nat Immunol . 2023 Feb; 24(3):452-462. PMID: 36823405
Exposure of lipopolysaccharide triggers macrophage pro-inflammatory polarization accompanied by metabolic reprogramming, characterized by elevated aerobic glycolysis and a broken tricarboxylic acid cycle. However, in contrast to lipopolysaccharide, CD40 signal is...
9.
Raines L, Zhao H, Wang Y, Chen H, Gallart-Ayala H, Hsueh P, et al.
Nat Immunol . 2022 Mar; 23(3):431-445. PMID: 35228694
Chronic inflammation triggers compensatory immunosuppression to stop inflammation and minimize tissue damage. Studies have demonstrated that endoplasmic reticulum (ER) stress augments the suppressive phenotypes of immune cells; however, the molecular...
10.
Yu Y, Imrichova H, Wang H, Chao T, Xiao Z, Gao M, et al.
Nat Immunol . 2020 Oct; 21(12):1540-1551. PMID: 33020660
The metabolic challenges present in tumors attenuate the metabolic fitness and antitumor activity of tumor-infiltrating T lymphocytes (TILs). However, it remains unclear whether persistent metabolic insufficiency can imprint permanent T...