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Przemyslaw Juszczynski

Explore the profile of Przemyslaw Juszczynski including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 2319
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Recent Articles
1.
Garbicz F, Kaszkowiak M, Dudkiewicz-Garbicz J, Dorfman D, Ostrowska J, Barankiewicz J, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596117
Multiple myeloma (MM) is a plasma cell malignancy that resides within the bone marrow microenvironment, relying heavily on interactions with its cellular components. Among these, endothelial cells (ECs) play a...
2.
Borek-Dorosz A, Nowakowska A, Laskowska P, Szydlowski M, Tipping W, Graham D, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2024 Apr; 1869(5):159496. PMID: 38649008
This work aims to understand better the mechanism of cellular processes accompanying the activation of human T cells and to develop a novel, fast, label-free approach to identify molecular biomarkers...
3.
Dawiec P, Leszczenko P, Nowakowska A, Laskowska P, Szydlowski M, Juszczynski P, et al.
Spectrochim Acta A Mol Biomol Spectrosc . 2024 Jan; 309:123795. PMID: 38184880
Diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin's lymphoma in adults, is a genetically and metabolically heterogeneous group of aggressive malignancies. The complexity of their molecular composition and the...
4.
Libura M, Karabin K, Tyrna P, Czyz A, Makuch-Lasica H, Jazwiec B, et al.
Cancers (Basel) . 2023 Nov; 15(22). PMID: 38001691
Adult acute lymphoblastic leukemia (ALL) is associated with poor outcomes. ALL is initiated by primary aberrations, but secondary genetic lesions are necessary for overt ALL. In this study, we reassessed...
5.
Bialopiotrowicz-Data E, Noyszewska-Kania M, Jablonska E, Sewastianik T, Komar D, Debek S, et al.
Cell Death Dis . 2023 Oct; 14(10):667. PMID: 37816710
Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin lymphoma in adults, exhibiting highly heterogenous clinical behavior and complex molecular background. In addition to the genetic complexity, different...
6.
Piechna K, Zolyniak A, Jablonska E, Noyszewska-Kania M, Szydlowski M, Zerek B, et al.
Front Oncol . 2022 Nov; 12:1048741. PMID: 36387080
Background: TRAIL (TNF-related apoptosis inducing ligand) exhibits selective proapoptotic activity in multiple tumor types, while sparing normal cells. This selectivity makes TRAIL an attractive therapeutic candidate. However, despite encouraging activity...
7.
Ramji K, Grzywa T, Sosnowska A, Paterek A, Okninska M, Pilch Z, et al.
Sci Rep . 2022 Nov; 12(1):19660. PMID: 36385153
Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite constantly evolving therapeutic approaches including various types of immunotherapy. Increased arginase activity has been associated with potent suppression of...
8.
Goral A, Firczuk M, Fidyt K, Sledz M, Simoncello F, Siudakowska K, et al.
Front Immunol . 2022 Mar; 13:781364. PMID: 35296093
Regulatory T cells (Tregs) are capable of inhibiting the proliferation, activation and function of T cells and play an important role in impeding the immune response to cancer. In chronic...
9.
Debek S, Juszczynski P
Biochim Biophys Acta Rev Cancer . 2022 Feb; 1877(2):188697. PMID: 35150791
Transcriptional deregulation of multiple oncogenes, tumor suppressors and survival pathways is a cancer cell hallmark. Super enhancers (SE) are long stretches of active enhancers in close linear proximity that ensure...
10.
Szlendak U, Krzymieniewska B, Mendek-Czajkowska E, Rogatko-Koros M, Witkowska A, Wlodarska J, et al.
Cytokine . 2021 Dec; 150:155780. PMID: 34896730
Objective: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal non-malignant disease in which hematopoietic cell apoptosis may play an important pathophysiological role. Previous studies of the content of phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P3)...