Prudence Donovan
Overview
Explore the profile of Prudence Donovan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
236
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0
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Recent Articles
1.
Donovan P, Patel J, Dight J, Wong H, Sim S, Murigneux V, et al.
Nat Commun
. 2019 Jan;
10(1):18.
PMID: 30604758
Tumor vascularization is a hallmark of cancer central to disease progression and metastasis. Current anti-angiogenic therapies have limited success prompting the need to better understand the cellular origin of tumor...
2.
Ginefra P, Filippi B, Donovan P, Bessonnard S, Constam D
Cell Rep
. 2018 Feb;
22(8):2176-2189.
PMID: 29466742
Furin trafficking, and that of related proprotein convertases (PCs), may regulate which substrates are accessible for endoproteolysis, but tools to directly test this hypothesis have been lacking. Here, we develop...
3.
Patel J, Donovan P, Khosrotehrani K
Oncotarget
. 2017 Nov;
8(49):84618-84619.
PMID: 29156660
No abstract available.
4.
Donovan P, Dubey O, Kallioinen S, Rogers K, Muehlethaler K, Muller P, et al.
J Invest Dermatol
. 2017 Aug;
137(12):2578-2587.
PMID: 28844941
The secreted growth factor Activin-A of the transforming growth factor β family and its receptors can promote or inhibit several cancer hallmarks including tumor cell proliferation and differentiation, vascularization, lymphangiogenesis...
5.
Shafiee A, Patel J, Wong H, Donovan P, Hutmacher D, Fisk N, et al.
FASEB J
. 2017 Jan;
31(2):610-624.
PMID: 28045376
The prospect of using endothelial progenitors is currently hampered by their low engraftment upon transplantation. We report that mesenchymal stem/stromal cells (MSCs), independent of source and age, improve the engraftment...
6.
Patel J, Seppanen E, Rodero M, Wong H, Donovan P, Neufeld Z, et al.
Circulation
. 2016 Dec;
135(8):786-805.
PMID: 27899395
Background: During adult life, blood vessel formation is thought to occur via angiogenic processes involving branching from existing vessels. An alternate proposal suggests that neovessels form from endothelial progenitors able...
7.
Patel J, Donovan P, Khosrotehrani K
Stem Cells Transl Med
. 2016 Jul;
5(10):1302-1306.
PMID: 27381992
Significance: The development of a therapy using endothelial progenitor cells provides great hope for patients in treating cardiovascular diseases going forward. For continual development of this therapy toward the clinical,...
8.
Donovan P, Cato K, Legaie R, Jayalath R, Olsson G, Hall B, et al.
Mol Biosyst
. 2014 Jan;
10(4):741-58.
PMID: 24448662
Here we report the identification of a proliferative, viable, and hyperdiploid tumor cell subpopulation present within Glioblastoma (GB) patient tumors. Using xenograft tumor models, we demonstrate that hyperdiploid cell populations...
9.
Donovan P, Poronnik P
Int J Biochem Cell Biol
. 2012 Dec;
45(3):706-10.
PMID: 23262292
Ubiquitination of proteins by the Nedd4 family of ubiquitin ligases is a significant mechanism in protein trafficking and degradation and provides for tight spatiotemporal regulation. Ubiquitination is gaining increasing recognition...