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Priyatha Premnath

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Articles 16
Citations 48
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Recent Articles
1.
Tavangar A, Premnath P, Tan B, Venkatakrishnan K
Biomed Mater . 2024 May; 19(4). PMID: 38772388
Biofouling is the most common cause of bacterial contamination in implanted materials/devices resulting in severe inflammation, implant mobilization, and eventual failure. Since bacterial attachment represents the initial step toward biofouling,...
2.
Premnath P, Lun T, Siddiqui H, Stahl A, Ardebili A, Olsen A, et al.
Calcif Tissue Int . 2024 Apr; 114(6):625-637. PMID: 38643416
Loss of p21 leads to increased bone formation post-injury; however, the mechanism(s) by which this occurs remains undetermined. E2f1 is downstream of p21 and as a transcription factor can act...
3.
Ferrie L, Premnath P, Olsen A, Larijani L, Besler B, Rancourt D, et al.
Sci Rep . 2023 Jun; 13(1):9378. PMID: 37296277
Promoting bone healing including fracture non-unions are promising targets for bone tissue engineering due to the limited success of current clinical treatment methods. There has been significant research on the...
4.
Ganesh S, Dhinakaran A, Premnath P, Venkatakrishnan K, Tan B
Bioengineering (Basel) . 2023 Mar; 10(3). PMID: 36978782
The recent COVID-19 pandemic has highlighted the inadequacies of existing diagnostic techniques and the need for rapid and accurate diagnostic systems. Although molecular tests such as RT-PCR are the gold...
5.
Shaikh A, Wesner A, Abuhattab M, Kutty R, Premnath P
Cell Biosci . 2023 Feb; 13(1):35. PMID: 36810262
Cell cycle regulators act as inhibitors or activators to prevent cancerogenesis. It has also been established that they can play an active role in differentiation, apoptosis, senescence, and other cell...
6.
Ewanchuk B, Arnold C, Balce D, Premnath P, Orsetti T, Warren A, et al.
Sci Adv . 2021 Apr; 7(17). PMID: 33893096
The extracellular bone resorbing lacuna of the osteoclast shares many characteristics with the degradative lysosome of antigen-presenting cells. γ-Interferon-inducible lysosomal thiol reductase (GILT) enhances antigen processing within lysosomes through direct...
7.
Abubacker S, Premnath P, Shonak A, Leonard C, Shah S, Zhu Y, et al.
J Orthop Res . 2019 May; 37(10):2077-2088. PMID: 31119776
Proteoglycan 4 (PRG4) is a mucin-like glycoprotein important for joint health. Mice lacking Prg4 demonstrate degeneration of the cartilage and altered skeletal morphology. The purpose of this study was to...
8.
Premnath P, Ferrie L, Louie D, Boyd S, Krawetz R
PLoS One . 2019 Apr; 14(4):e0215018. PMID: 30970032
p21(WAF1/CIP1/SDI1) is a critical sentinel of the cell cycle that plays an important role in determining cell fate with respect to proliferation, differentiation and apoptosis. Recent studies have demonstrated that...
9.
Premnath P, Jorgenson B, Hess R, Tailor P, Louie D, Taiani J, et al.
BMC Musculoskelet Disord . 2017 Nov; 18(1):435. PMID: 29121899
Background: p21, a cyclin dependent kinase inhibitor has been shown to influence cell proliferation, differentiation and apoptosis; but more recently, p21 has been implicated in tissue repair. Studies on p21()...
10.
Tavangar A, Premnath P, Tan B, Venkatakrishnan K
ACS Appl Mater Interfaces . 2016 Apr; 8(16):10253-65. PMID: 27035281
Nanomaterials have proven to possess great potential in biomaterials research. Recently, they have suggested considerable promise in cancer diagnosis and therapy. Among others, silicon (Si) nanomaterials have been extensively employed...